HOOK1 and HOOK3

Number of citations of the paper that reports this interaction (PMID 18799622)
9

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		HOOK1	HOOK3
Gene Name		hook microtubule-tethering protein 1	hook microtubule-tethering protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule HOPS Complex FHF Complex	Pericentriolar Material Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Microtubule Organizing Center Microtubule HOPS Complex Centriolar Satellite FHF Complex
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Protein Binding Microtubule Binding Identical Protein Binding
	Biological Process	Endosome Organization Lysosome Organization Multicellular Organismal Development Spermatid Development Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Maintenance
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AKTIP ANK3 CDC5L CDK4 FAM160A2 HOOK2 HOOK3 LMO2 SYCE1 TBC1D7 TFIP11 USP2 VPS16 VPS18 VPS39 VPS41 ZNF250 ZNF785	5 interactors: AKTIP HOOK1 HOOK2 VPS16 VPS41
Entrez ID		51361	84376
HPRD ID		07428	09699
Ensembl ID		ENSG00000134709	ENSG00000168172
Uniprot IDs		Q9UJC3	Q86VS8
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Endosomal Transport Intracellular Transport Endomembrane System Organization Regulation Of Vesicle Fusion Protein Localization Vesicle-mediated Transport Establishment Of Localization In Cell Cytoplasmic Transport Cellular Localization Organelle Organization Cellular Protein Localization Intracellular Protein Transport Viral Entry Into Host Cell Entry Into Host Cell Maintenance Of Protein Location In Plasma Membrane Regulation Of Vacuole Fusion, Non-autophagic Spliceosomal Complex Disassembly Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Vacuole Fusion, Non-autophagic Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Cell Communication By Electrical Coupling Regulation Of Protein Complex Assembly Negative Regulation Of Cilium Assembly Cell Cycle Regulation Of Vesicle-mediated Transport Interaction With Host Cellular Response To Magnesium Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Membrane Depolarization During Action Potential Regulation Of Organelle Organization Maintenance Of Protein Location In Cell Transport Maintenance Of Protein Location Regulation Of Cardiac Muscle Cell Action Potential Maintenance Of Location In Cell Regulation Of Delayed Rectifier Potassium Channel Activity Cell Cycle Process Circadian Rhythm	Vacuolar Transport Vacuole Organization Early Endosome To Late Endosome Transport Endosome To Lysosome Transport Endosome Organization Endosomal Transport Lysosomal Transport Lysosome Organization Protein Transport Regulation Of SNARE Complex Assembly Establishment Of Protein Localization Intracellular Transport Protein Localization Cytoplasmic Transport Establishment Of Localization In Cell Cellular Localization Regulation Of Vesicle Fusion Endomembrane System Organization Vesicle-mediated Transport Regulation Of Vacuole Fusion, Non-autophagic Vacuole Fusion, Non-autophagic Transport Organelle Organization Regulation Of Protein Complex Assembly Regulation Of Vesicle-mediated Transport Regulation Of Vacuole Organization Protein Targeting To Vacuole Establishment Of Protein Localization To Vacuole Viral Entry Into Host Cell Entry Into Host Cell Intracellular Protein Transport Regulation Of Organelle Organization Positive Regulation Of Protein Binding Organelle Fusion Interaction With Host
Tagcloud ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated	akt1 akt2 aurka axon card11 deregulated exclusive exome fgfr2 grouping integrative massively men1 mlf1 mutually nets neuroendocrine nono pdgfr preponderance provisional recurrently si smad smad1 snvs therapeutically transitions vhl
Tagcloud (Difference) ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated	akt1 akt2 aurka axon card11 deregulated exclusive exome fgfr2 grouping integrative massively men1 mlf1 mutually nets neuroendocrine nono pdgfr preponderance provisional recurrently si smad smad1 snvs therapeutically transitions vhl
Tagcloud (Intersection) ?