AKTIP and VPS16

Number of citations of the paper that reports this interaction (PMID 18799622)
9

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		AKTIP	VPS16
Gene Name		AKT interacting protein	vacuolar protein sorting 16 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Golgi Apparatus Plasma Membrane HOPS Complex FHF Complex	Lysosome Lysosomal Membrane Early Endosome Late Endosome Actin Filament Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	Actin Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Apoptotic Process Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Protein Ubiquitination Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport	Intracellular Protein Transport Endosomal Transport Regulation Of Vacuole Fusion, Non-autophagic Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: AKT1 ASS1 C10orf2 CTBP2 DZIP3 EXOC7 FAM160A2 GTF3C1 HOOK1 HOOK2 HOOK3 IMMT KIAA1377 MARCH5 PDPK1 POLA2 RPA1 TRIM23 TRIM41 UTP14A VPS16 VPS18 VPS41	10 interactors: AKTIP HOOK1 HOOK2 HOOK3 MON1B STX7 UVRAG VPS11 VPS18 VPS33A
Entrez ID		64400	64601
HPRD ID		07467	12259
Ensembl ID		ENSG00000166971	ENSG00000215305
Uniprot IDs		Q9H8T0	Q9H269
PDB IDs			4BX9
Enriched GO Terms of Interacting Partners?		Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Protein Localization Organelle Organization Endosomal Transport Endomembrane System Organization Cytoplasmic Transport Cellular Localization Intracellular Transport Establishment Of Localization In Cell Regulation Of Vesicle Fusion Protein Localization To Organelle DNA-dependent DNA Replication Telomere Maintenance Via Semi-conservative Replication Protein Ubiquitination Cellular Protein Localization Nuclear DNA Replication Telomere Maintenance Via Recombination Protein Modification By Small Protein Conjugation Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Response To Epidermal Growth Factor Stimulus Vesicle-mediated Transport Positive Regulation Of Protein Localization To Plasma Membrane Response To Epidermal Growth Factor Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Protein Import Into Nucleus, Translocation Regulation Of Vesicle-mediated Transport DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening G1/S Transition Of Mitotic Cell Cycle Response To Fluid Shear Stress Cytoplasmic Microtubule Organization Viral Entry Into Host Cell Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Temperature Stimulus Viral Life Cycle Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Entry Into Host Cell Argininosuccinate Metabolic Process Regulation Of Vacuole Fusion, Non-autophagic	Endosome Organization Vesicle-mediated Transport Lysosome Organization Early Endosome To Late Endosome Transport Vacuole Organization Endosome To Lysosome Transport Lysosomal Transport Protein Transport Establishment Of Protein Localization Vacuolar Transport Protein Localization Establishment Of Localization In Cell Transport Cellular Localization Intracellular Transport Endomembrane System Organization Endosomal Transport Vesicle Docking Membrane Docking Organelle Organization Viral Entry Into Host Cell Cytoplasmic Transport Entry Into Host Cell Vesicle Fusion Vesicle Docking Involved In Exocytosis Organelle Fusion Positive Regulation Of Receptor Localization To Synapse Organelle Localization Interaction With Host Membrane Fusion Cellular Protein Localization Viral Life Cycle Regulation Of SNARE Complex Assembly Vesicle Organization SNARE Complex Assembly Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Protein Localization To Centrosome Golgi Localization Interkinetic Nuclear Migration Exocytosis Protein Localization To Cytoskeleton Platelet Formation Platelet Morphogenesis Regulation Of Developmental Pigmentation Regulation Of Vesicle-mediated Transport Neuronal Stem Cell Maintenance Lysosome Localization Positive Regulation Of Autophagy
Tagcloud ?		apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works	adherens anxb9 apical appearance b9 basolateral boundary colocalizations coracle cytoskeleton destabilization disrupting dlg endosomal eps15 fidelity intimately karst multivesicular mvb pak redistribution segregation shotgun spectrin spliceoforms ubiquitylated vesicles zonula
Tagcloud (Difference) ?		apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works	adherens anxb9 apical appearance b9 basolateral boundary colocalizations coracle cytoskeleton destabilization disrupting dlg endosomal eps15 fidelity intimately karst multivesicular mvb pak redistribution segregation shotgun spectrin spliceoforms ubiquitylated vesicles zonula
Tagcloud (Intersection) ?