HOOK1 and VPS16

Number of citations of the paper that reports this interaction (PMID 18799622)
9

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		HOOK1	VPS16
Gene Name		hook microtubule-tethering protein 1	vacuolar protein sorting 16 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule HOPS Complex FHF Complex	Lysosome Lysosomal Membrane Early Endosome Late Endosome Actin Filament Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Actin Binding Actin Filament Binding
	Biological Process	Endosome Organization Lysosome Organization Multicellular Organismal Development Spermatid Development Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport	Intracellular Protein Transport Endosomal Transport Regulation Of Vacuole Fusion, Non-autophagic Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AKTIP ANK3 CDC5L CDK4 FAM160A2 HOOK2 HOOK3 LMO2 SYCE1 TBC1D7 TFIP11 USP2 VPS16 VPS18 VPS39 VPS41 ZNF250 ZNF785	10 interactors: AKTIP HOOK1 HOOK2 HOOK3 MON1B STX7 UVRAG VPS11 VPS18 VPS33A
Entrez ID		51361	64601
HPRD ID		07428	12259
Ensembl ID		ENSG00000134709	ENSG00000215305
Uniprot IDs		Q9UJC3	Q9H269
PDB IDs			4BX9
Enriched GO Terms of Interacting Partners?		Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Endosomal Transport Intracellular Transport Endomembrane System Organization Regulation Of Vesicle Fusion Protein Localization Vesicle-mediated Transport Establishment Of Localization In Cell Cytoplasmic Transport Cellular Localization Organelle Organization Cellular Protein Localization Intracellular Protein Transport Viral Entry Into Host Cell Entry Into Host Cell Maintenance Of Protein Location In Plasma Membrane Regulation Of Vacuole Fusion, Non-autophagic Spliceosomal Complex Disassembly Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Vacuole Fusion, Non-autophagic Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Cell Communication By Electrical Coupling Regulation Of Protein Complex Assembly Negative Regulation Of Cilium Assembly Cell Cycle Regulation Of Vesicle-mediated Transport Interaction With Host Cellular Response To Magnesium Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Membrane Depolarization During Action Potential Regulation Of Organelle Organization Maintenance Of Protein Location In Cell Transport Maintenance Of Protein Location Regulation Of Cardiac Muscle Cell Action Potential Maintenance Of Location In Cell Regulation Of Delayed Rectifier Potassium Channel Activity Cell Cycle Process Circadian Rhythm	Endosome Organization Vesicle-mediated Transport Lysosome Organization Early Endosome To Late Endosome Transport Vacuole Organization Endosome To Lysosome Transport Lysosomal Transport Protein Transport Establishment Of Protein Localization Vacuolar Transport Protein Localization Establishment Of Localization In Cell Transport Cellular Localization Intracellular Transport Endomembrane System Organization Endosomal Transport Vesicle Docking Membrane Docking Organelle Organization Viral Entry Into Host Cell Cytoplasmic Transport Entry Into Host Cell Vesicle Fusion Vesicle Docking Involved In Exocytosis Organelle Fusion Positive Regulation Of Receptor Localization To Synapse Organelle Localization Interaction With Host Membrane Fusion Cellular Protein Localization Viral Life Cycle Regulation Of SNARE Complex Assembly Vesicle Organization SNARE Complex Assembly Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Protein Localization To Centrosome Golgi Localization Interkinetic Nuclear Migration Exocytosis Protein Localization To Cytoskeleton Platelet Formation Platelet Morphogenesis Regulation Of Developmental Pigmentation Regulation Of Vesicle-mediated Transport Neuronal Stem Cell Maintenance Lysosome Localization Positive Regulation Of Autophagy
Tagcloud ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated	adherens anxb9 apical appearance b9 basolateral boundary colocalizations coracle cytoskeleton destabilization disrupting dlg endosomal eps15 fidelity intimately karst multivesicular mvb pak redistribution segregation shotgun spectrin spliceoforms ubiquitylated vesicles zonula
Tagcloud (Difference) ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated	adherens anxb9 apical appearance b9 basolateral boundary colocalizations coracle cytoskeleton destabilization disrupting dlg endosomal eps15 fidelity intimately karst multivesicular mvb pak redistribution segregation shotgun spectrin spliceoforms ubiquitylated vesicles zonula
Tagcloud (Intersection) ?