PSEN1 and ERN1

  • Number of citations of the paper that reports this interaction (PMID 10587643)
  • 59
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

PSEN1

ERN1

Gene Name presenilin 1 endoplasmic reticulum to nucleus signaling 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 91 interactors: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DLL1 DOCK3 DSP ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RHEB RMDN3 RNF32 SCAF11 SCN1A ST13 STAMBPL1 TCF4 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1 14 interactors: BAK1 BAX COPS5 HSP90AA1 HSPA5 MAP3K5 PSEN1 SRPK2 STUB1 SYVN1 TAOK3 TNFRSF1A TRAF2 UBC
Entrez ID 5663 2081
HPRD ID 00087 04943
Ensembl ID ENSG00000080815 ENSG00000178607
Uniprot IDs P49768 O75460
PDB IDs 2KR6 2HZ6 3P23
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
blockade  correlates  depends  deubiquitinates  e3  effector  endoplasmic  endoribonuclease  erni  glioma  homolog  hypoxia  hypoxic  intensified  knockdown  ligase  mdm2  nuclei  ofmdm2  peptidase  perp  repression  reticulum  suppression  tp53  u87  ubiquitin  ups7  usp7 
Tagcloud (Difference) ?
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
blockade  correlates  depends  deubiquitinates  e3  effector  endoplasmic  endoribonuclease  erni  glioma  homolog  hypoxia  hypoxic  intensified  knockdown  ligase  mdm2  nuclei  ofmdm2  peptidase  perp  repression  reticulum  suppression  tp53  u87  ubiquitin  ups7  usp7 
Tagcloud (Intersection) ?