PSEN1 and MAPT

  • Number of citations of the paper that reports this interaction (PMID 9689133)
  • 50

PSEN1

MAPT

Gene Name presenilin 1 microtubule-associated protein tau
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 91 interactors: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DLL1 DOCK3 DSP ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RHEB RMDN3 RNF32 SCAF11 SCN1A ST13 STAMBPL1 TCF4 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1 78 interactors: AATF ABL1 ACTB AKT1 APOE APP ARHGEF40 BAG1 CALM1 CAMK2A CAPN2 CASP1 CASP3 CASP6 CASP7 CASP8 CDK1 CDK2 CDK5 CDK5R1 CSNK1A1 CSNK1D CSNK2A1 EP300 FYN GSK3A GSK3B HSPA4 HSPA8 LRRK2 MAPK11 MAPK12 MAPK13 MAPK8 MARCH7 MARK1 MARK2 MARK3 MARK4 OGT PEG10 PHKG1 PIN1 PKN1 PPP2CA PPP2CB PPP2R4 PPP2R5A PPP5C PRKACA PRKAR1A PRKCD PSEN1 PTK2B RPS6KA1 RPS6KA3 RPS6KA5 RPS6KB1 S100B SGK1 SIRT1 SNCA SPTB SRC STAU1 STUB1 STXBP1 SYK TRAF6 TUBA1B TUBA4A TUBB UBB UBC UBE2D2 USP9Y YWHAB YWHAZ
Entrez ID 5663 4137
HPRD ID 00087 01142
Ensembl ID ENSG00000080815 ENSG00000186868
Uniprot IDs P49768 B3KTM0 P10636
PDB IDs 2KR6 1I8H 3FQP 3OVL 4GLR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  neuropathological  pd  psen1  publically  publication  shifted  tar  variants 
Tagcloud (Difference) ?
Tagcloud (Intersection) ?
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  psen1  publically  publication  shifted  tar  variants