PSEN1 and PDCD4

  • Number of citations of the paper that reports this interaction (PMID 21163940)
  • 13
  • Data Source:
  • BioGRID (two hybrid)

PSEN1

PDCD4

Gene Name presenilin 1 programmed cell death 4 (neoplastic transformation inhibitor)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 91 interactors: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DLL1 DOCK3 DSP ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RHEB RMDN3 RNF32 SCAF11 SCN1A ST13 STAMBPL1 TCF4 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1 12 interactors: APOE BTRC CSNK2A1 EIF4A2 EIF4A3 EIF4G1 PSEN1 PSEN2 RPL5 RPLP1 RPS13 RPS6KA1
Entrez ID 5663 27250
HPRD ID 00087 10549
Ensembl ID ENSG00000080815 ENSG00000150593
Uniprot IDs P49768 B4DKX4 Q53EL6
PDB IDs 2KR6 2GGF 2KZT 2RG8 2ZU6 3EIJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
classes  constituents  cycling  cyclins  dexd  dysregulation  eif4a  eif4a1  eif4b  eif4e  helicase  helicases  impede  mcf7  microrna  motors  oncogenic  otherwise  pcdc4  polysome  preferential  quadruplexes  ribosome  structured  translatome  ubiquitous  unwind  unwinding  utrs 
Tagcloud (Difference) ?
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
classes  constituents  cycling  cyclins  dexd  dysregulation  eif4a  eif4a1  eif4b  eif4e  helicase  helicases  impede  mcf7  microrna  motors  oncogenic  otherwise  pcdc4  polysome  preferential  quadruplexes  ribosome  structured  translatome  ubiquitous  unwind  unwinding  utrs 
Tagcloud (Intersection) ?