PSEN1 and RHEB

  • Number of citations of the paper that reports this interaction (PMID 21163940)
  • 13
  • Data Source:
  • BioGRID (two hybrid)

PSEN1

RHEB

Gene Name presenilin 1 Ras homolog enriched in brain
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 91 interactors: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DLL1 DOCK3 DSP ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RHEB RMDN3 RNF32 SCAF11 SCN1A ST13 STAMBPL1 TCF4 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1 22 interactors: A2M APOE ARIH2 ATM ATR BNIP3 BNIP3L BRAF ECSIT FKBP8 MTOR NCAM1 PDE6D PLD1 PSEN1 PSEN2 RABAC1 RAF1 RPS6KB1 RPTOR TSC1 TSC2
Entrez ID 5663 6009
HPRD ID 00087 03188
Ensembl ID ENSG00000080815 ENSG00000106615
Uniprot IDs P49768 Q15382
PDB IDs 2KR6 1XTQ 1XTR 1XTS 3SEA 3T5G
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
abovementioned  altogether  amls  angiomyolipomas  carry  chronically  comparative  deficient  diminished  farnesylthiosalicylic  fts  indeed  irf7  lam  lymphangioleiomyomatosis  mimicked  mtorc1  neoplasms  pathologies  phenomena  rapamycin  salirasib  sirolimus  sporadic  trans  tsc  tsc2  tuberous  yielded 
Tagcloud (Difference) ?
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
abovementioned  altogether  amls  angiomyolipomas  carry  chronically  comparative  deficient  diminished  farnesylthiosalicylic  fts  indeed  irf7  lam  lymphangioleiomyomatosis  mimicked  mtorc1  neoplasms  pathologies  phenomena  rapamycin  salirasib  sirolimus  sporadic  trans  tsc  tsc2  tuberous  yielded 
Tagcloud (Intersection) ?