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TNNI3K and ACTC1
Number of citations of the paper that reports this interaction (PMID
12721663
)
9
Data Source:
HPRD
(two hybrid)
TNNI3K
ACTC1
Gene Name
TNNI3 interacting kinase
actin, alpha, cardiac muscle 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Extracellular Space
Cytoplasm
Cytosol
Actin Filament
Focal Adhesion
Membrane
Sarcomere
I Band
Actomyosin, Actin Portion
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Troponin I Binding
Metal Ion Binding
ATP Binding
ATPase Activity
Myosin Binding
Biological Process
Protein Phosphorylation
Apoptotic Process
Metabolic Process
Actin Filament-based Movement
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Actomyosin Structure Organization
Actin-myosin Filament Sliding
Response To Drug
Negative Regulation Of Apoptotic Process
Response To Ethanol
Cardiac Myofibril Assembly
Cardiac Muscle Tissue Morphogenesis
Heart Contraction
Cardiac Muscle Contraction
Pathways
Striated Muscle Contraction
Drugs
Diseases
GWAS
Body mass index (
23669352
20935630
)
Obesity (
23563607
)
Pubertal anthropometrics (
23449627
)
Prostate cancer (gene x gene interaction) (
22219177
)
Refractive error (
20835239
)
Protein-Protein Interactions
7 interactors:
ACTA1
ACTC1
AIP
FABP3
HADHB
MYBPC3
TNNI3
35 interactors:
ABLIM3
ABRA
ACTB
ACTN4
ACTR2
AFAP1
ANG
BCL11A
CAPN1
CFL1
DMD
DMTN
DYNLL1
EZR
FSCN1
GAPDH
GC
HSPB1
KLHL17
KLHL2
KPTN
LASP1
MIB2
MPC1
MYLK
PLEC
PRKCE
SCIN
SLC4A1
SYNE1
SYNE2
TNNI3K
TWF1
WAS
WIPF1
Entrez ID
51086
70
HPRD ID
18208
00015
Ensembl ID
ENSG00000116783
ENSG00000159251
Uniprot IDs
Q59H18
B3KPP5
P68032
PDB IDs
Enriched GO Terms of Interacting Partners
?
Actin-myosin Filament Sliding
Muscle Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Muscle Contraction
Cardiac Muscle Contraction
Cardiac Muscle Tissue Morphogenesis
Muscle System Process
Muscle Tissue Morphogenesis
Muscle Organ Development
Heart Contraction
Muscle Organ Morphogenesis
Striated Muscle Tissue Development
Myofibril Assembly
Skeletal Muscle Thin Filament Assembly
Muscle Tissue Development
Striated Muscle Contraction
Skeletal Myofibril Assembly
Actomyosin Structure Organization
Muscle Structure Development
Striated Muscle Cell Development
Muscle Cell Development
Cardiac Muscle Tissue Development
Actin Filament-based Process
Heart Morphogenesis
Striated Muscle Cell Differentiation
Regulation Of ATPase Activity
Ventricular Cardiac Muscle Tissue Morphogenesis
Blood Circulation
Muscle Cell Differentiation
Ventricular Cardiac Muscle Tissue Development
Cardiac Ventricle Morphogenesis
Organelle Assembly
Heart Development
Cardiac Ventricle Development
Movement Of Cell Or Subcellular Component
Actin Cytoskeleton Organization
Skeletal Muscle Fiber Adaptation
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Tissue Morphogenesis
Cardiac Chamber Development
Tissue Development
Regulation Of Muscle Contraction
Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Regulation Of Muscle Filament Sliding
Myosin Filament Assembly
Cardiovascular System Development
Positive Regulation Of Phospholipid Biosynthetic Process
Cardiolipin Acyl-chain Remodeling
Long-chain Fatty Acid Import
Actin Filament-based Process
Actin Cytoskeleton Organization
Cytoskeleton Organization
Actin Filament Organization
Organelle Organization
Movement Of Cell Or Subcellular Component
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Cellular Component Size
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Cytoskeleton Organization
Regulation Of Actin Cytoskeleton Organization
Cellular Component Assembly
Regulation Of Actin Filament-based Process
Regulation Of Cellular Component Organization
Actin Filament-based Movement
Phagocytosis
Blood Coagulation
Fc Receptor Signaling Pathway
Hemostasis
Cellular Localization
Actin Filament Bundle Assembly
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Organelle Organization
Regulation Of Actin Filament Polymerization
Actin Polymerization Or Depolymerization
Regulation Of Protein Complex Assembly
Platelet Activation
Regulation Of Sodium Ion Transmembrane Transporter Activity
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Cytoskeleton Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Regulation Of Sodium Ion Transmembrane Transport
Wound Healing
Positive Regulation Of Organelle Organization
Vesicle-mediated Transport
Endocytosis
Nucleus Localization
Negative Regulation Of Protein Complex Assembly
Maintenance Of Protein Location In Cell
Cell Activation
Positive Regulation Of Wound Healing
Maintenance Of Protein Location
Immune Response-regulating Signaling Pathway
Maintenance Of Location In Cell
Response To Wounding
Cell Projection Assembly
Tagcloud
?
accompany
ach3
ach4
cardiac
cardiomyocytes
cardiomyogenic
cd29
commitment
cscs
elusive
fate
hdac
hdac1
hdac2
hypothesize
indicative
loci
mark
modifications
mscs
myh6
myl2
noticed
possess
sca
stronger
tnni3
tnnt2
trichostatin
Tagcloud (Difference)
?
accompany
ach3
ach4
cardiac
cardiomyocytes
cardiomyogenic
cd29
commitment
cscs
elusive
fate
hdac
hdac1
hdac2
hypothesize
indicative
loci
mark
modifications
mscs
myh6
myl2
noticed
possess
sca
stronger
tnni3
tnnt2
trichostatin
Tagcloud (Intersection)
?