TNNI3K and AIP

Number of citations of the paper that reports this interaction (PMID 12721663)
9

Data Source:
HPRD (two hybrid)

		TNNI3K	AIP
Gene Name		TNNI3 interacting kinase	aryl hydrocarbon receptor interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein C-terminus Binding Troponin I Binding Metal Ion Binding	Transcription Coactivator Activity Signal Transducer Activity Protein Binding Transcription Factor Binding GAF Domain Binding Unfolded Protein Binding
	Biological Process	Protein Phosphorylation	Protein Targeting To Mitochondrion Xenobiotic Metabolic Process Signal Transduction Regulation Of Protein Kinase A Signaling Protein Maturation By Protein Folding Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Body mass index ( 23669352 20935630) Obesity ( 23563607) Pubertal anthropometrics ( 23449627)
Protein-Protein Interactions		7 interactors: ACTA1 ACTC1 AIP FABP3 HADHB MYBPC3 TNNI3	16 interactors: AHR ARNT CLEC7A CSNK2A1 EGFR GNA13 GNAQ HSP90AA1 IKBKG IRF7 PDE4A PPARA PTGES3 STIP1 TNNI3K TOMM20
Entrez ID		51086	9049
HPRD ID		18208	10408
Ensembl ID		ENSG00000116783	ENSG00000110711
Uniprot IDs		Q59H18	O00170
PDB IDs			2LKN 4AIF 4APO
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Muscle Contraction Cardiac Muscle Contraction Cardiac Muscle Tissue Morphogenesis Muscle System Process Muscle Tissue Morphogenesis Muscle Organ Development Heart Contraction Muscle Organ Morphogenesis Striated Muscle Tissue Development Myofibril Assembly Skeletal Muscle Thin Filament Assembly Muscle Tissue Development Striated Muscle Contraction Skeletal Myofibril Assembly Actomyosin Structure Organization Muscle Structure Development Striated Muscle Cell Development Muscle Cell Development Cardiac Muscle Tissue Development Actin Filament-based Process Heart Morphogenesis Striated Muscle Cell Differentiation Regulation Of ATPase Activity Ventricular Cardiac Muscle Tissue Morphogenesis Blood Circulation Muscle Cell Differentiation Ventricular Cardiac Muscle Tissue Development Cardiac Ventricle Morphogenesis Organelle Assembly Heart Development Cardiac Ventricle Development Movement Of Cell Or Subcellular Component Actin Cytoskeleton Organization Skeletal Muscle Fiber Adaptation Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Tissue Morphogenesis Cardiac Chamber Development Tissue Development Regulation Of Muscle Contraction Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Muscle Filament Sliding Myosin Filament Assembly Cardiovascular System Development Positive Regulation Of Phospholipid Biosynthetic Process Cardiolipin Acyl-chain Remodeling Long-chain Fatty Acid Import	Intracellular Receptor Signaling Pathway Signal Transduction Response To Stress Signaling Cell Communication Immune Response-regulating Signaling Pathway Regulation Of Immune System Process Positive Regulation Of Metabolic Process Cellular Response To Stimulus Positive Regulation Of Phospholipase Activity Response To Stimulus Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Rhythmic Process Protein Refolding Response To External Stimulus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Catenin Import Into Nucleus Activation Of Innate Immune Response Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Glycolytic Process Regulation Of Cellular Response To Heat Circadian Rhythm Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Innate Immune Response Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Gene Expression Negative Regulation Of Cell Death Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Activation Of Phospholipase C Activity Response To Abiotic Stimulus Regulation Of Innate Immune Response Cellular Response To Drug Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Phospholipase C Activity Positive Regulation Of Immune Response Fc Receptor Signaling Pathway Alkanesulfonate Metabolic Process Regulation Of Glycolytic By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Nitric Oxide Biosynthetic Process Protein Transmembrane Transport Toll-like Receptor 9 Signaling Pathway
Tagcloud ?			aminolaevulinate aspect autosomal coproporphyria counterparts cutanea decarboxylase dehydratase develops elucidating hepatoerythropoietic hereditary heteroallelic homo inherited intermittent mutational overt pct porphyria porphyrias puberty rarely recessive tarda uncommon uroporphyrinogen variegate vp
Tagcloud (Difference) ?			aminolaevulinate aspect autosomal coproporphyria counterparts cutanea decarboxylase dehydratase develops elucidating hepatoerythropoietic hereditary heteroallelic homo inherited intermittent mutational overt pct porphyria porphyrias puberty rarely recessive tarda uncommon uroporphyrinogen variegate vp
Tagcloud (Intersection) ?