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PCBD2 and ASCC2
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
PCBD2
ASCC2
Gene Name
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
activating signal cointegrator 1 complex subunit 2
Image
Gene Ontology Annotations
Cellular Component
Cellular_component
Nucleus
Mitochondrion
Molecular Function
Phenylalanine 4-monooxygenase Activity
Protein Binding
4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
Biological Process
Tetrahydrobiopterin Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Protein Homotetramerization
Protein Heterooligomerization
Oxidation-reduction Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Bulimia nervosa (
23568457
)
Colorectal cancer (
23263487
)
Height (
18391951
)
Protein-Protein Interactions
31 interactors:
AATF
APP
ASCC2
BRF1
C1D
CDC5L
CENPK
CHAF1A
GTF2E1
HES4
IRF2BP1
KCNIP3
MAGEA11
MED21
MED30
MED4
MED7
MET
PBXIP1
PCBD1
PHF14
PML
RUNX1T1
SNW1
SSX3
SSX5
STAT3
TAL2
TGIF2LY
XBP1
ZZZ3
38 interactors:
ASS1
CKAP4
CUTC
DEAF1
EEF1D
ELAC2
FAF1
FBP1
FUNDC2
GADD45A
GFER
GNL3
GTF3C1
IGSF9
IMMT
JUN
KDM1A
LPL
MED31
MYH9
OLA1
PCBD2
PIK3CD
PIN4
PJA1
POLA2
POLDIP2
RADIL
RELA
RNF11
RPA1
RPLP1
SNRPB
SNW1
SRF
TBC1D17
TRIP4
URM1
Entrez ID
84105
84164
HPRD ID
17824
16515
Ensembl ID
ENSG00000100325
Uniprot IDs
Q9H0N5
Q9H1I8
PDB IDs
4C45
2DI0
Enriched GO Terms of Interacting Partners
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Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Positive Regulation Of Transcription, DNA-templated
Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Apoptotic Process
Negative Regulation Of Gene Expression
Programmed Cell Death
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Cell Death
Death
Stem Cell Maintenance
Transcription From RNA Polymerase II Promoter
Cell Differentiation
Positive Regulation Of Histone Modification
Negative Regulation Of Cell Differentiation
Stem Cell Development
Developmental Process
Positive Regulation Of Metabolic Process
Regulation Of Cell Differentiation
Cellular Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Myeloid Leukocyte Differentiation
RNA Metabolic Process
Nitrogen Compound Metabolic Process
Myeloid Cell Differentiation
Nucleobase-containing Compound Metabolic Process
Transcription From RNA Polymerase II Promoter
Positive Regulation By Host Of Viral Transcription
Leukocyte Differentiation
RNA Biosynthetic Process
Metabolic Process
Response To Abiotic Stimulus
Mitochondrion Organization
Hemopoiesis
Monocyte Differentiation
Transcription, DNA-templated
Telomere Maintenance Via Semi-conservative Replication
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Platelet Formation
Protein Tetramerization
Response To Radiation
Platelet Morphogenesis
Immune System Development
Macromolecule Biosynthetic Process
Telomere Maintenance Via Recombination
Regulation Of Histone H3-K4 Methylation
Nuclear DNA Replication
Positive Regulation Of Transcription, DNA-templated
Response To CAMP
Mitotic Recombination
DNA Strand Elongation Involved In DNA Replication
Response To Drug
DNA Strand Elongation
Telomere Maintenance Via Telomere Lengthening
Response To Stress
Gene Expression
Blood Vessel Endothelial Cell Migration
Interaction With Symbiont
Learning
Membrane Protein Proteolysis
Aging
Regulation Of Cell Proliferation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Response To Organophosphorus
Positive Regulation Of Macromolecule Biosynthetic Process
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