PCBD2 and BRF1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PCBD2	BRF1
Gene Name		pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Nucleus Mitochondrion	Transcription Factor TFIIIB Complex Nucleoplasm
	Molecular Function	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity	Zinc Ion Binding TBP-class Protein Binding
	Biological Process	Tetrahydrobiopterin Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Protein Homotetramerization Protein Heterooligomerization Oxidation-reduction Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Gene Expression Regulation Of MRNA Stability
Pathways			RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 18391951)	Mean platelet volume ( 22139419)
Protein-Protein Interactions		31 interactors: AATF APP ASCC2 BRF1 C1D CDC5L CENPK CHAF1A GTF2E1 HES4 IRF2BP1 KCNIP3 MAGEA11 MED21 MED30 MED4 MED7 MET PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3	13 interactors: APP CSNK2A1 DTNBP1 GTF3C3 GTF3C4 GTF3C5 PCBD2 POLR3F RB1 RBL1 RBL2 TBP TP53
Entrez ID		84105	2972
HPRD ID		17824	05361
Ensembl ID			ENSG00000185024
Uniprot IDs		Q9H0N5	Q92994
PDB IDs		4C45
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Apoptotic Process Negative Regulation Of Gene Expression Programmed Cell Death Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Cell Death Death Stem Cell Maintenance Transcription From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Histone Modification Negative Regulation Of Cell Differentiation Stem Cell Development Developmental Process Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation	Transcription From RNA Polymerase III Promoter RRNA Transcription 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter TRNA Transcription Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Biosynthetic Process Macromolecule Biosynthetic Process Neuron Apoptotic Process Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Neuron Death Positive Regulation Of Gene Expression Regulation Of Cell Cycle Phase Transition Glial Cell Apoptotic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Chromatin Organization Mitotic Cell Cycle Positive Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Checkpoint Regulation Of RNA Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cell Cycle Process Regulation Of Metabolic Process Neuron Maturation Chromosome Organization Regulation Of Chromosome Organization Viral Process Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation
Tagcloud ?			5s alcohol cjun colony consumption decreases deregulation downregulate enhances eralpha iii indicates inhibits jun occupancy pol promoters reduces repress repressing repression rrna tam tamoxifen transcription translational trnas uncover upregulate
Tagcloud (Difference) ?			5s alcohol cjun colony consumption decreases deregulation downregulate enhances eralpha iii indicates inhibits jun occupancy pol promoters reduces repress repressing repression rrna tam tamoxifen transcription translational trnas uncover upregulate
Tagcloud (Intersection) ?