Gene Name |
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 |
MET proto-oncogene, receptor tyrosine kinase |
Image |
|
|
Gene Ontology Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
- K-252a
- 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide
- N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide
- 2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide
- N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide
- 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol
- 6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline
- 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine
- 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE
- Cabozantinib
|
Diseases |
|
|
GWAS |
|
- Multiple sclerosis (severity) ( 19010793)
|
Protein-Protein Interactions |
31 interactors:
AATF
APP
ASCC2
BRF1
C1D
CDC5L
CENPK
CHAF1A
GTF2E1
HES4
IRF2BP1
KCNIP3
MAGEA11
MED21
MED30
MED4
MED7
MET
PBXIP1
PCBD1
PHF14
PML
RUNX1T1
SNW1
SSX3
SSX5
STAT3
TAL2
TGIF2LY
XBP1
ZZZ3
|
37 interactors:
BAG1
CASP3
CBL
CNR1
CTNNB1
CTTN
DAPK3
DCN
DNAJA3
EGFR
FAS
GAB1
GLMN
GRB2
HGF
HGS
INPP5D
INPPL1
ITGB4
MUC20
PCBD2
PIK3R1
PLCG1
PLXNB1
PTPN11
PTPRB
PTPRJ
RANBP10
RANBP9
SHC1
SMC1A
SNAPIN
SNX2
SPSB1
SRC
STAT3
VAV1
|
Entrez ID |
84105 |
4233 |
HPRD ID |
17824 |
01280 |
Ensembl ID |
|
ENSG00000105976
|
Uniprot IDs |
Q9H0N5
|
B4DLF5
P08581
|
PDB IDs |
4C45
|
1FYR
1R0P
1R1W
1SHY
1SSL
1UX3
2G15
2RFN
2RFS
2UZX
2UZY
2WD1
2WGJ
2WKM
3A4P
3BUX
3C1X
3CCN
3CD8
3CE3
3CTH
3CTJ
3DKC
3DKF
3DKG
3EFJ
3EFK
3F66
3F82
3I5N
3L8V
3LQ8
3Q6U
3Q6W
3QTI
3R7O
3RHK
3U6H
3U6I
3VW8
3ZXZ
3ZZE
4AOI
4AP7
4DEG
4DEH
4DEI
4EEV
4GG5
4GG7
4K3J
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
basophil
basophils
c5a
ccr2
ccr3
chains
chemoattractant
chemotactic
continuous
continuously
cxcr1
cxcr2
eotaxin
express
fmlp
formyl
granulocyte
hardly
leu
leukotrienes
lt
ltc4
macrophage
mcp
mcp1
mediate
migratory
phe
unrelated
weakly
|
Tagcloud (Difference) ? |
|
basophil
basophils
c5a
ccr2
ccr3
chains
chemoattractant
chemotactic
continuous
continuously
cxcr1
cxcr2
eotaxin
express
fmlp
formyl
granulocyte
hardly
leu
leukotrienes
lt
ltc4
macrophage
mcp
mcp1
mediate
migratory
phe
unrelated
weakly
|
Tagcloud (Intersection) ? |
|