CHIC2 and CDR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CHIC2	CDR2
Description		cysteine rich hydrophobic domain 2	cerebellar degeneration related protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Golgi-associated Vesicle Plasma Membrane Membrane Cytoplasmic Vesicle	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Metabolite levels ( 23823483) Post bronchodilator FEV1/FVC ratio ( 26634245) Pulse pressure ( 28739976 30487518) Serum metabolite levels (CMS) ( 31636271) Subcortical volume (MOSTest) ( 32665545)	Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		68 interacting genes: ADAMTSL4 AGXT AXIN2 C1QTNF2 CARD10 CATSPER1 CBY2 CDR2 CEP44 CYSRT1 DNAL4 FBLN1 GMCL1 HOXA1 ITSN2 KANK2 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP6-2 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2C LCE3A LCE3C LCE3D LCE3E LCE5A LCN2 LZTS2 MDFI MEOX2 MTUS2 MYF5 MYPOP NBPF19 NDUFB7 NOTCH2NLA OTX1 PLEKHF1 PLEKHF2 PLEKHG4 PNMA1 POU4F2 PPARA REL SCNM1 SDCBP TCF4 TOP3B TUBGCP4 U2AF2 ZNF330 ZNF837	76 interacting genes: AMOTL2 ANKRD36BP1 AQP1 ARNT2 BEX2 C1orf216 C4orf46 CATSPERT CCDC120 CCDC13 CCDC146 CCDC187 CCDC87 CCHCR1 CDC20 CEP57L1 CHIC2 COX5B DRC12 DRC4 EIF4E2 ENKD1 FAM110A FAM161A FAM50B FAM90A1 FXR1 FZR1 GEM GMPPA HAUS1 HDAC4 HGS KANSL1 KIF5B KIFC3 LENG1 LIN37 MICALL2 MKKS MNS1 MORF4L2 MRPL28 NDN NTAQ1 OAZ2 PKN1 PRKAA2 PRPF18 PSMA1 RCOR3 RSPH14 RUNX1T1 SCNM1 SH2D4A SMARCD1 SMARCE1 TBC1D22B TCHP TEAD4 TEX28 TMCC2 TRIM23 TRIML2 TSC1 TSGA10IP TTC23 TTR TXLNA TXLNB UBTFL1 ZGPAT ZMAT2 ZNF250 ZNF35 ZNF417
Entrez ID		26511	1039
HPRD ID		10373	06681
Ensembl ID		ENSG00000109220	ENSG00000140743
Uniprot IDs		Q9UKJ5	Q01850
PDB IDs		8SUV
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Regulation Of Transformation Of Host Cell By Virus Protein Binding	Protein Binding Centrosome Cytoskeleton Ciliary Basal Body Microtubule Cytoskeleton Organization Microtubule-based Process Motile Cilium Cytoplasm Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Microtubule Binding Cilium Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Cytoskeleton Organization Cell Projection Cilium Organization Polymeric Cytoskeletal Fiber
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