CHIC2 and U2AF2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHIC2	U2AF2
Gene Name		cysteine-rich hydrophobic domain 2	U2 small nuclear RNA auxiliary factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Golgi-associated Vesicle Plasma Membrane	Prp19 Complex Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	Molecular_function Protein Binding	Nucleotide Binding Protein Binding Enzyme Binding Poly(A) RNA Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Golgi To Plasma Membrane Transport Biological_process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS		Blood pressure ( 21909110)
Protein-Protein Interactions		26 interactors: CATSPER1 CDR2 CEP44 GMCL1 HOXA1 ITSN2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 MDFI MEOX2 NOTCH2NL OTX1 PLEKHF2 PNMA1 SPERT TCF4 TOP3B TUBGCP4 U2AF2	51 interactors: AES APBB1 ATXN1 BEND7 CCAR1 CHERP CHIC2 CPSF7 DACH1 DDX17 DDX6 DPPA2 DVL2 EPB41 GEMIN2 GLIS2 HLA-DMA HNRNPA0 HNRNPD HNRNPK IL7R KHDRBS1 KHDRBS3 KIAA0907 LURAP1 MAP1B PIN1 POLR2A PRPF3 PRPF40A PUF60 QKI RBFOX2 RBM39 RBM4 SAP30BP SCAF11 SF1 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SUGP1 TCERG1 THAP1 TOP1 U2AF1 WT1 ZRSR2
Entrez ID		26511	11338
HPRD ID		10373	01872
Ensembl ID		ENSG00000109220	ENSG00000063244
Uniprot IDs		Q9UKJ5	P26368
PDB IDs			1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW
Enriched GO Terms of Interacting Partners?		Embryonic Organ Morphogenesis Pattern Specification Process Embryonic Organ Development Anterior/posterior Pattern Specification Embryo Development Embryonic Morphogenesis Optokinetic Behavior Abducens Nerve Formation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Facial Nucleus Development Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Diencephalon Development Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Inner Ear Morphogenesis Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Rhombomere 4 Development Semicircular Canal Formation Developmental Process Rhombomere 3 Development Rhombomere 5 Development Maintenance Of DNA Repeat Elements Positive Regulation Of Metabolic Process Embryonic Skeletal System Morphogenesis Ear Morphogenesis Organ Morphogenesis Metencephalon Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Somite Specification Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Blood Vessel Development Multicellular Organismal Development Regulation Of Transcription From RNA Polymerase II Promoter Vasculature Development Diencephalon Morphogenesis Embryonic Genitalia Morphogenesis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Embryonic Skeletal System Development Myoblast Fate Commitment Hindbrain Development Single Organism Reproductive Process Embryonic Neurocranium Morphogenesis Secretory Granule Localization	RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Biosynthetic Process Spliceosomal Complex Assembly Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Biogenesis Cellular Macromolecular Complex Assembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Metabolic Process Regulation Of MRNA Processing Termination Of RNA Polymerase II Transcription Regulation Of MRNA Stability Regulation Of RNA Stability Cellular Process DNA-templated Transcription, Termination Regulation Of Translation MRNA 3'-end Processing Positive Regulation Of Macromolecule Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Female Gonad Development Circadian Regulation Of Translation RNA 3'-end Processing
Tagcloud ?			acceptor accessory advance alters codons corroborated cytidine doi junctions leu missense november novo online publication q157 q157p q157r s34 s34f s34y seq snrnp speckles splice splicing u2af1 uridine
Tagcloud (Difference) ?			acceptor accessory advance alters codons corroborated cytidine doi junctions leu missense november novo online publication q157 q157p q157r s34 s34f s34y seq snrnp speckles splice splicing u2af1 uridine
Tagcloud (Intersection) ?