KRTAP10-8 and PTPRH

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP10-8	PTPRH
Description		keratin associated protein 10-8	protein tyrosine phosphatase receptor type H
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Cytoplasm Cytosol Plasma Membrane Microvillus Membrane Apical Plasma Membrane Nuclear Speck Microvillus Membrane Cell Projection
	Molecular Function	Protein Binding Identical Protein Binding	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Cadherin Binding
	Biological Process		Protein Dephosphorylation Apoptotic Process Signal Transduction Axon Guidance
Pathways		Keratinization
Drugs
Diseases
GWAS			Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 27863252 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite levels ( 33031748) Systemic lupus erythematosus ( 28714469)
Interacting Genes		400 interacting genes: ACY3 ADAM12 ADAMTS1 ADAMTSL3 ADAMTSL4 AEBP2 AEN AK3 ALDH3B1 ALPI ALPP AMMECR1 ANKS1A ANXA2R-AS1 AP1M1 APOL6 AQP1 AREG ARHGAP33 ARID5A ASPSCR1 ATG9A ATP5F1D AVPI1 AXIN2 BAHD1 BCL6B BEX2 BMP7 BRME1 C10orf62 C11orf87 C17orf50 C19orf25 C22orf39 C2orf68 C3 CAMK1G CARD10 CARHSP1 CATSPER1 CCDC26 CCNJL CHIC2 CHRD CHRNG CLK4 CNNM3 COL8A1 COX17 CRCT1 CREB5 CRH CRY2 CSF1 CST2 CTRC CYP2S1 CYSRT1 DAAM2 DCX DDX43 DDX55 DDX6 DERL2 DHRS1 DHX57 DMRT3 DOCK2 ECE1 EFEMP2 EIF4E2 ENKD1 EPDR1 FADS6 FAH FAM110A FAM161A FAM221B FAM27E3 FAM74A4 FAM76B FAM90A1 FARS2 FBXO34 FBXW5 FEZF1 FOXB1 FRS3 FTHL17 FZD10 GARIN6 GEM GFOD1 GLIDR GLP1R GLRX3 GLYAT GNAI2 GNE GOLGA8EP GPANK1 GPHB5 GPRIN2 GRN GUCD1 HAPLN2 HCK HHEX HOXA1 HOXB5 HOXB9 HOXC8 HPCAL1 HS6ST1 HSD3B7 HSPA12B HSPD1 ICAM1 IGFBP6 IGSF8 IL10 IL16 IL2RG INO80B INS INTS5 IP6K3 ITGB2 ITGB4 ITGB5 JOSD1 JPH3 KCNS2 KLHL38 KLK8 KPRP KRT20 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-2 KRTAP15-1 KRTAP17-1 KRTAP19-7 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 KSR2 LAGE3 LASP1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LENG1 LINC00656 LMF2 LNX1 LRCH4 LRFN4 LUZP4 LYVE1 MACROH2A1 MAPKBP1 MATN3 MEIS2 MELTF MEOX2 MLLT6 MOBP MTA1 MTNR1A MUL1 MXD3 MXI1 MYPOP NAB2 NAXD NBPF19 NECTIN2 NECTIN3 NEK6 NKD1 NOTCH2NLA NPDC1 NR1D2 NR4A3 NTN4 NUFIP2 OLIG3 OPCML OTX1 P2RX7 P2RY6 PAX5 PCED1A PCSK5 PDE9A PDIA4 PGAP6 PGLS PHLDA1 PIGS PIN1 PKD2 PLA2G10 PLSCR4 POM121L8P POU1F1 POU4F2 PRF1 PRKAB2 PRPF31 PRR13 PRR19 PTGER3 PTK7 PTPMT1 PTPRH PVR QPRT R3HDM2 RAB19 RAB3A RALGDS RANBP3 RASD1 RECK RGL2 RHBDL1 RHNO1 RNF38 RNF8 RPS19BP1 RPS28 RTN4RL1 SCARF1 SCNM1 SEMA3B SH3GLB2 SHFL SLC13A5 SLC22A23 SLC23A1 SLC25A10 SLC25A31 SLC25A42 SLC6A20 SLIT1 SMARCE1 SMCP SMG9 SMOC1 SPACA9 SPAG8 SPATA24 SPATA3 SPRY1 SPRY2 SSC4D STK16 SUSD2 SUSD6 SUV39H1 TACSTD2 TAPBPL TBC1D16 TBC1D23 TCAF1 TCEA2 TCEANC TFAP2D TGFB1 THAP10 THAP7 TIE1 TLE5 TMEM140 TMEM150A TMIE TNIP3 TNP2 TNPO3 TNS2 TRIM41 TRIM42 TRPV6 TSPAN4 TTC23 TXNDC5 TYMSOS TYRO3 UBL5 UTP23 UXT VASN VENTX VEZF1 VGLL3 VPS11 VWC2 VWC2L WIF1 WNT11 WT1 WT1-AS YIPF3 YY1 ZBTB24 ZBTB25 ZDHHC1 ZFYVE21 ZIC1 ZNF101 ZNF107 ZNF121 ZNF124 ZNF138 ZNF165 ZNF20 ZNF23 ZNF250 ZNF264 ZNF266 ZNF319 ZNF32 ZNF330 ZNF408 ZNF414 ZNF417 ZNF419 ZNF439 ZNF440 ZNF444 ZNF473 ZNF490 ZNF491 ZNF497 ZNF524 ZNF559 ZNF572 ZNF575 ZNF578 ZNF580 ZNF581 ZNF587 ZNF625 ZNF648 ZNF669 ZNF696 ZNF697 ZNF775 ZNF786 ZNF79 ZNF792 ZNF837 ZSCAN12 ZSCAN21	16 interacting genes: BCAR1 CNKSR1 CRK DHPS DOK1 EGFR ERBB3 ERBB4 GHR KRTAP10-3 KRTAP10-8 LCK MAPK1 MLH1 PTK2 PXN
Entrez ID		386681	5794
HPRD ID		11194	03942
Ensembl ID		ENSG00000187766	ENSG00000080031
Uniprot IDs		P60410	Q9HD43
PDB IDs			7XC0
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratin Filament Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Zinc Ion Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Hair Cycle Tissue Development RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Axis Elongation Sequence-specific Double-stranded DNA Binding	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway ERBB2 Signaling Pathway Cell Surface Receptor Signaling Pathway Protein Phosphatase Binding SH2 Domain Binding Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activator Activity Signal Transduction Regulation Of MAPK Cascade Growth Hormone Receptor Signaling Pathway Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Positive Regulation Of MAPK Cascade Protein Kinase Activity Positive Regulation Of Macrophage Proliferation Response To Growth Factor Phosphotyrosine Residue Binding Cell Migration Positive Regulation Of Cell Population Proliferation Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Kinase Activity Response To Epidermal Growth Factor B Cell Receptor Signaling Pathway Signal Complex Assembly ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Cell Motility Receptor Complex Basal Plasma Membrane Immune Response-regulating Signaling Pathway Focal Adhesion Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Immune System Process Positive Regulation Of Protein Phosphorylation Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Growth Positive Regulation Of Phosphorylation Response To Hepatocyte Growth Factor Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Communication Positive Regulation Of Signaling Immune Response-regulating Cell Surface Receptor Signaling Pathway Schwann Cell Development Positive Regulation Of Cell Migration T Cell Receptor Signaling Pathway
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