KRTAP10-8 and TNIP3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-8	TNIP3
Gene Name		keratin associated protein 10-8	TNFAIP3 interacting protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament
	Molecular Function		Polyubiquitin Binding
	Biological Process		MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS			Breast cancer ( 23468962)
Protein-Protein Interactions		163 interactors: ACY3 ADAMTSL3 ADAMTSL4 AEN AES ALDH3B1 ALPI APOL6 ASPSCR1 ATG9A BEX2 BMP7 C11orf87 C19orf66 C9orf9 CARHSP1 CARKD CATSPER1 CCDC26 CCNJL CHIC2 CHRD CHRNG CLK4 CNNM3 COL8A1 CRCT1 CREB5 DAAM2 DCX DDX55 DDX6 DERL2 DHRS1 DHX57 DMRT3 DOCK2 EIF4E2 FAH FAM27E3 FAM74A4 FAM76B FBXW5 FOXB1 GFOD1 GLIDR GLP1R GLRX3 GLYAT GNAI2 GNE GOLGA8EP HHEX HOXA1 HPCAL1 HSD3B7 HSPD1 IGSF8 ITGB5 JOSD1 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LINC00656 LOC153684 LRCH4 LUZP4 LYVE1 MAPKBP1 MATN3 MEOX2 MLLT6 MTA1 MXI1 NAB2 NOTCH2NL NUFIP2 OTX1 P2RX7 PCED1A PCSK5 PDE9A PGLS PIGS PKD2 POM121L8P PRKAB2 PRPF31 PRR13 PTGER3 PTPMT1 PTPRH PVR PVRL3 QPRT R3HDM2 RANBP3 RPS28 RTN4RL1 SCNM1 SLC22A23 SLC23A1 SLC25A10 SLC6A20 SMCP SMOC1 SPATA3 SPRY1 SPRY2 STK16 SUSD6 TBC1D16 TBC1D23 THAP10 THAP7 TMEM150A TNIP3 TNP2 TNS2 TRPV6 TXNDC5 TYMSOS TYRO3 UTP23 UXT VPS11 WIF1 WT1 WT1-AS YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF138 ZNF20 ZNF32 ZNF417 ZNF439 ZNF473 ZNF572 ZNF578 ZNF587 ZNF697 ZSCAN21	11 interactors: DAZAP2 KRT40 KRTAP10-3 KRTAP10-8 LZTS2 NOTCH2NL TAX1BP1 TNFAIP3 TNIP1 UBC ZBTB8A
Entrez ID		386681	79931
HPRD ID		11194	16268
Ensembl ID		ENSG00000187766	ENSG00000050730
Uniprot IDs		P60410	Q96KP6
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization RNA Biosynthetic Process Transcription, DNA-templated Gene Expression RNA Metabolic Process Pattern Specification Process Keratinocyte Differentiation Organ Development Epithelium Development Cellular Nitrogen Compound Metabolic Process Developmental Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Development Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Epidermis Development Tissue Development Negative Regulation Of Glomerulus Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Epidermal Cell Differentiation Macromolecule Biosynthetic Process Metanephric Mesenchyme Development Heterocycle Metabolic Process Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Sperm Motility Negative Regulation Of Cell Proliferation Involved In Kidney Development Fertilization Biosynthetic Process Anterior/posterior Pattern Specification Anatomical Structure Development Epithelial Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Metanephric S-shaped Body Morphogenesis Single Fertilization System Development Branching Morphogenesis Of An Epithelial Tube Regulation Of Glomerular Mesangial Cell Proliferation Penetration Of Zona Pellucida S-shaped Body Morphogenesis Positive Regulation Of Immune Response To Tumor Cell Floor Plate Development Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Tube Development Skin Development Bud Elongation Involved In Lung Branching Morphogenesis Of A Branching Epithelium Negative Regulation Of Mesenchymal Cell Apoptotic Process Epithelial Tube Branching Involved In Lung Morphogenesis Morphogenesis Of A Branching Structure	Negative Regulation Of Type I Interferon Production Regulation Of Type I Interferon Production Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Negative Regulation Of Cytokine Production Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Innate Immune Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Signal Transduction Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Signaling MyD88-dependent Toll-like Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Negative Regulation Of CD40 Signaling Pathway Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Defense Response Regulation Of Cytokine Production Negative Regulation Of Protein Ubiquitination Toll-like Receptor Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Osteoclast Proliferation Tolerance Induction To Lipopolysaccharide Positive Regulation Of Immune Response Notch Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Regulation Of CD40 Signaling Pathway Protein Polyubiquitination Regulation Of Vascular Wound Healing Positive Regulation Of Hepatocyte Proliferation Negative Regulation Of Chronic Inflammatory Response Innate Immune Response Negative Regulation Of Wnt Signaling Pathway Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Regulation Of Immune Response Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway B-1 B Cell Homeostasis Positive Regulation Of Protein Catabolic Process Positive Regulation Of Immune System Process
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