KRTAP10-8 and LYVE1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-8	LYVE1
Gene Name		keratin associated protein 10-8	lymphatic vessel endothelial hyaluronan receptor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function		Receptor Activity Transmembrane Signaling Receptor Activity Hyaluronic Acid Binding
	Biological Process		Carbohydrate Metabolic Process Transport Movement Of Cell Or Subcellular Component Cell-matrix Adhesion Signal Transduction Pathogenesis Response To Wounding Anatomical Structure Morphogenesis Glycosaminoglycan Metabolic Process Hyaluronan Metabolic Process Hyaluronan Catabolic Process Small Molecule Metabolic Process
Pathways			MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Hyaluronan uptake and degradation Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Glycogen storage diseases MPS IIID - Sanfilippo syndrome D Hyaluronan metabolism Defective CHST6 causes MCDC1 MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS Metabolism of carbohydrates MPS VII - Sly syndrome MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-Protein Interactions		163 interactors: ACY3 ADAMTSL3 ADAMTSL4 AEN AES ALDH3B1 ALPI APOL6 ASPSCR1 ATG9A BEX2 BMP7 C11orf87 C19orf66 C9orf9 CARHSP1 CARKD CATSPER1 CCDC26 CCNJL CHIC2 CHRD CHRNG CLK4 CNNM3 COL8A1 CRCT1 CREB5 DAAM2 DCX DDX55 DDX6 DERL2 DHRS1 DHX57 DMRT3 DOCK2 EIF4E2 FAH FAM27E3 FAM74A4 FAM76B FBXW5 FOXB1 GFOD1 GLIDR GLP1R GLRX3 GLYAT GNAI2 GNE GOLGA8EP HHEX HOXA1 HPCAL1 HSD3B7 HSPD1 IGSF8 ITGB5 JOSD1 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LINC00656 LOC153684 LRCH4 LUZP4 LYVE1 MAPKBP1 MATN3 MEOX2 MLLT6 MTA1 MXI1 NAB2 NOTCH2NL NUFIP2 OTX1 P2RX7 PCED1A PCSK5 PDE9A PGLS PIGS PKD2 POM121L8P PRKAB2 PRPF31 PRR13 PTGER3 PTPMT1 PTPRH PVR PVRL3 QPRT R3HDM2 RANBP3 RPS28 RTN4RL1 SCNM1 SLC22A23 SLC23A1 SLC25A10 SLC6A20 SMCP SMOC1 SPATA3 SPRY1 SPRY2 STK16 SUSD6 TBC1D16 TBC1D23 THAP10 THAP7 TMEM150A TNIP3 TNP2 TNS2 TRPV6 TXNDC5 TYMSOS TYRO3 UTP23 UXT VPS11 WIF1 WT1 WT1-AS YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF138 ZNF20 ZNF32 ZNF417 ZNF439 ZNF473 ZNF572 ZNF578 ZNF587 ZNF697 ZSCAN21	4 interactors: KRTAP10-3 KRTAP10-8 PDGFB VEGFA
Entrez ID		386681	10894
HPRD ID		11194	05753
Ensembl ID		ENSG00000187766
Uniprot IDs		P60410	B2R672 F2Z296 Q9Y5Y7
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization RNA Biosynthetic Process Transcription, DNA-templated Gene Expression RNA Metabolic Process Pattern Specification Process Keratinocyte Differentiation Organ Development Epithelium Development Cellular Nitrogen Compound Metabolic Process Developmental Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Development Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Epidermis Development Tissue Development Negative Regulation Of Glomerulus Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Epidermal Cell Differentiation Macromolecule Biosynthetic Process Metanephric Mesenchyme Development Heterocycle Metabolic Process Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Sperm Motility Negative Regulation Of Cell Proliferation Involved In Kidney Development Fertilization Biosynthetic Process Anterior/posterior Pattern Specification Anatomical Structure Development Epithelial Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Metanephric S-shaped Body Morphogenesis Single Fertilization System Development Branching Morphogenesis Of An Epithelial Tube Regulation Of Glomerular Mesangial Cell Proliferation Penetration Of Zona Pellucida S-shaped Body Morphogenesis Positive Regulation Of Immune Response To Tumor Cell Floor Plate Development Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Tube Development Skin Development Bud Elongation Involved In Lung Branching Morphogenesis Of A Branching Epithelium Negative Regulation Of Mesenchymal Cell Apoptotic Process Epithelial Tube Branching Involved In Lung Morphogenesis Morphogenesis Of A Branching Structure	Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Chemotaxis Regulation Of Protein Autophosphorylation Positive Regulation Of Kidney Development Regulation Of Blood Vessel Endothelial Cell Migration Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Endothelial Cell Proliferation Platelet Degranulation Positive Regulation Of Epithelial Cell Migration Regulation Of Endothelial Cell Proliferation Leukocyte Chemotaxis Regulation Of Endothelial Cell Migration Positive Regulation Of Chemotaxis Positive Regulation Of Cell Division Positive Regulation Of Behavior Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Chemotaxis Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cell Chemotaxis Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Behavior Regulation Of ERK1 And ERK2 Cascade Platelet Activation Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Kinase D Signaling Metanephric Glomerular Mesangial Cell Development Metanephric Glomerular Endothelium Development Basophil Chemotaxis Positive Regulation Of MAP Kinase Activity Leukocyte Migration Morphogenesis Of A Branching Epithelium Regulation Of Cell Division Morphogenesis Of A Branching Structure Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Epithelial Cell Proliferation Regulation Of MAP Kinase Activity Response To Hypoxia Metanephric Glomerular Mesangial Cell Differentiation Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Positive Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Protein Localization To Early Endosome Negative Regulation Of Phosphatidylinositol Biosynthetic Process Paracrine Signaling Cellular Response To Mycophenolic Acid Positive Regulation Of Retinal Ganglion Cell Axon Guidance
Tagcloud ?			cd31 collects consist cyst diminish disfiguring enlarged hd hyper implicate lec lm ly294 lymphatic malformation malformations microcystic overgrowth pi3 pik3r3 podoplanin prox1 sclerotherapy sprouting stop surgically thr308 wortmannin
Tagcloud (Difference) ?			cd31 collects consist cyst diminish disfiguring enlarged hd hyper implicate lec lm ly294 lymphatic malformation malformations microcystic overgrowth pi3 pik3r3 podoplanin prox1 sclerotherapy sprouting stop surgically thr308 wortmannin
Tagcloud (Intersection) ?