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KRTAP10-8 and P2RX7
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRTAP10-8
P2RX7
Gene Name
keratin associated protein 10-8
purinergic receptor P2X, ligand gated ion channel, 7
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Integral Component Of Nuclear Inner Membrane
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
External Side Of Plasma Membrane
Membrane
Neuromuscular Junction
Bleb
Neuronal Cell Body
Terminal Bouton
Protein Complex
Membrane Raft
Molecular Function
Magnesium Ion Binding
Lipopolysaccharide Binding
Purinergic Nucleotide Receptor Activity
Extracellular ATP-gated Cation Channel Activity
Receptor Binding
Copper Ion Binding
Protein Binding
ATP Binding
Zinc Ion Binding
Protein Homodimerization Activity
Scaffold Protein Binding
Biological Process
Activation Of MAPK Activity
Cell Morphogenesis
Phagolysosome Assembly
Positive Regulation Of T Cell Mediated Cytotoxicity
Regulation Of Sodium Ion Transport
Protein Phosphorylation
Membrane Protein Ectodomain Proteolysis
Phospholipid Transfer To Membrane
Cell Volume Homeostasis
Membrane Budding
Inflammatory Response
Mitochondrion Organization
Plasma Membrane Organization
Cell Surface Receptor Signaling Pathway
Response To Mechanical Stimulus
Response To Zinc Ion
Positive Regulation Of Calcium Ion Transport Into Cytosol
Positive Regulation Of Glutamate Secretion
Positive Regulation Of Gamma-aminobutyric Acid Secretion
Synaptic Vesicle Exocytosis
Protein Processing
Neuronal Action Potential
Sensory Perception Of Pain
Cytolysis
Positive Regulation Of Bone Mineralization
Cellular Response To Extracellular Stimulus
Bleb Assembly
Positive Regulation Of Prostaglandin Secretion
Response To Lipopolysaccharide
Positive Regulation Of Interleukin-6 Production
Collagen Metabolic Process
Response To ATP
Response To Fluid Shear Stress
Purinergic Nucleotide Receptor Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
T Cell Proliferation
Response To Drug
T Cell Homeostasis
NAD Transport
Negative Regulation Of MAPK Cascade
Multicellular Organismal Protein Catabolic Process
Innate Immune Response
Phospholipid Translocation
Negative Regulation Of Bone Resorption
Positive Regulation Of Cytolysis
Ceramide Biosynthetic Process
Pore Complex Assembly
Skeletal System Morphogenesis
Homeostasis Of Number Of Cells Within A Tissue
Positive Regulation Of Interleukin-1 Alpha Secretion
Positive Regulation Of Interleukin-1 Beta Secretion
Defense Response To Gram-positive Bacterium
Release Of Sequestered Calcium Ion Into Cytosol
Protein Oligomerization
Positive Regulation Of Cytoskeleton Organization
Response To Calcium Ion
Response To Electrical Stimulus
Regulation Of Killing Of Cells Of Other Organism
Membrane Depolarization
Positive Regulation Of Mitochondrial Depolarization
Positive Regulation Of Lymphocyte Apoptotic Process
Reactive Oxygen Species Metabolic Process
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway
Cation Transmembrane Transport
Pathways
The NLRP3 inflammasome
Inflammasomes
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
Innate Immune System
Drugs
Diseases
GWAS
Chronic obstructive pulmonary disease-related biomarkers (
23144326
)
Protein-Protein Interactions
163 interactors:
ACY3
ADAMTSL3
ADAMTSL4
AEN
AES
ALDH3B1
ALPI
APOL6
ASPSCR1
ATG9A
BEX2
BMP7
C11orf87
C19orf66
C9orf9
CARHSP1
CARKD
CATSPER1
CCDC26
CCNJL
CHIC2
CHRD
CHRNG
CLK4
CNNM3
COL8A1
CRCT1
CREB5
DAAM2
DCX
DDX55
DDX6
DERL2
DHRS1
DHX57
DMRT3
DOCK2
EIF4E2
FAH
FAM27E3
FAM74A4
FAM76B
FBXW5
FOXB1
GFOD1
GLIDR
GLP1R
GLRX3
GLYAT
GNAI2
GNE
GOLGA8EP
HHEX
HOXA1
HPCAL1
HSD3B7
HSPD1
IGSF8
ITGB5
JOSD1
KLHL38
KRT20
KRT83
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE3C
LCE3E
LCE4A
LINC00656
LOC153684
LRCH4
LUZP4
LYVE1
MAPKBP1
MATN3
MEOX2
MLLT6
MTA1
MXI1
NAB2
NOTCH2NL
NUFIP2
OTX1
P2RX7
PCED1A
PCSK5
PDE9A
PGLS
PIGS
PKD2
POM121L8P
PRKAB2
PRPF31
PRR13
PTGER3
PTPMT1
PTPRH
PVR
PVRL3
QPRT
R3HDM2
RANBP3
RPS28
RTN4RL1
SCNM1
SLC22A23
SLC23A1
SLC25A10
SLC6A20
SMCP
SMOC1
SPATA3
SPRY1
SPRY2
STK16
SUSD6
TBC1D16
TBC1D23
THAP10
THAP7
TMEM150A
TNIP3
TNP2
TNS2
TRPV6
TXNDC5
TYMSOS
TYRO3
UTP23
UXT
VPS11
WIF1
WT1
WT1-AS
YIPF3
ZBTB24
ZFYVE21
ZNF124
ZNF138
ZNF20
ZNF32
ZNF417
ZNF439
ZNF473
ZNF572
ZNF578
ZNF587
ZNF697
ZSCAN21
9 interactors:
ACTB
CASK
EFNB3
EMP3
KRT31
KRTAP10-8
PANX1
SVIL
TM9SF1
Entrez ID
386681
5027
HPRD ID
11194
03977
Ensembl ID
ENSG00000187766
ENSG00000089041
Uniprot IDs
P60410
Q99572
PDB IDs
Enriched GO Terms of Interacting Partners
?
Keratinization
RNA Biosynthetic Process
Transcription, DNA-templated
Gene Expression
RNA Metabolic Process
Pattern Specification Process
Keratinocyte Differentiation
Organ Development
Epithelium Development
Cellular Nitrogen Compound Metabolic Process
Developmental Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Epidermis Development
Tissue Development
Negative Regulation Of Glomerulus Development
Negative Regulation Of Glomerular Mesangial Cell Proliferation
Epidermal Cell Differentiation
Macromolecule Biosynthetic Process
Metanephric Mesenchyme Development
Heterocycle Metabolic Process
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Sperm Motility
Negative Regulation Of Cell Proliferation Involved In Kidney Development
Fertilization
Biosynthetic Process
Anterior/posterior Pattern Specification
Anatomical Structure Development
Epithelial Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Metanephric S-shaped Body Morphogenesis
Single Fertilization
System Development
Branching Morphogenesis Of An Epithelial Tube
Regulation Of Glomerular Mesangial Cell Proliferation
Penetration Of Zona Pellucida
S-shaped Body Morphogenesis
Positive Regulation Of Immune Response To Tumor Cell
Floor Plate Development
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Tube Development
Skin Development
Bud Elongation Involved In Lung Branching
Morphogenesis Of A Branching Epithelium
Negative Regulation Of Mesenchymal Cell Apoptotic Process
Epithelial Tube Branching Involved In Lung Morphogenesis
Morphogenesis Of A Branching Structure
Tagcloud
?
adam29
cd109
cd248
cgh
chl1
cladogram
crcs
csmd3
ercc6
ergic3
evl
fbxw7
galns
gnas
iranian
lgr
mmp2
msi
msp
mss
parsimony
prkd1
ptprd
rnf182
sfrs6
slc29a1
specifics
syne1
tbx22
Tagcloud (Difference)
?
adam29
cd109
cd248
cgh
chl1
cladogram
crcs
csmd3
ercc6
ergic3
evl
fbxw7
galns
gnas
iranian
lgr
mmp2
msi
msp
mss
parsimony
prkd1
ptprd
rnf182
sfrs6
slc29a1
specifics
syne1
tbx22
Tagcloud (Intersection)
?