KRTAP5-9 and P2RX4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP5-9	P2RX4
Gene Name		keratin associated protein 5-9	purinergic receptor P2X, ligand gated ion channel, 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Integral Component Of Nuclear Inner Membrane Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Membrane Cell Junction Neuronal Cell Body Terminal Bouton Dendritic Spine Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Purinergic Nucleotide Receptor Activity Extracellular ATP-gated Cation Channel Activity Receptor Binding Copper Ion Binding ATP Binding Drug Binding Zinc Ion Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Epidermis Development	Tissue Homeostasis Regulation Of Sodium Ion Transport Nitric Oxide Biosynthetic Process Transport Calcium Ion Transport Signal Transduction Regulation Of Blood Pressure Positive Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Cardiac Muscle Hypertrophy Neuronal Action Potential Sensory Perception Of Pain Positive Regulation Of Prostaglandin Secretion Response To ATP Ion Transmembrane Transport Response To Fluid Shear Stress Purinergic Nucleotide Receptor Signaling Pathway Endothelial Cell Activation Vasodilation Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Calcium-mediated Signaling Protein Homooligomerization Membrane Depolarization Positive Regulation Of Calcium Ion Transport Regulation Of Cardiac Muscle Contraction Relaxation Of Cardiac Muscle Regulation Of Excitatory Postsynaptic Membrane Potential Cellular Response To ATP Apoptotic Signaling Pathway Cation Transmembrane Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		103 interactors: ADAMTSL4 ALPP ATG9A BEX2 BMP7 C10orf62 C11orf87 C19orf66 CARKD CATSPER1 CHIC2 CHRD CKS1B CNNM3 COMT CRCT1 CTSZ CXCL16 DHRS1 DMRT3 DOCK2 FAH FAM124B FAM161A FAM74A4 FAM76B GLRX3 GNE HOXA1 HOXB9 HPCAL1 HSPD1 JOSD1 KLHL38 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE3C LCE3E LCE4A LY6H MAPKBP1 MEOX2 NCLN NLK NMU NOTCH2NL NPBWR2 NPDC1 NTM NTN4 NUFIP2 OTX1 P2RX4 PCSK5 PFKL PGLS POM121L8P PRKAB2 PSMA1 PTPMT1 PVRL2 RAMP3 RGS20 RNF111 SCARB1 SDC3 SDCBP SLC22A23 SLC25A10 SMCP SPINK2 SPRY2 TBC1D10C TBC1D16 TCEA2 TCEANC TOMM22 TYRO3 WDYHV1 YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF266 ZNF417 ZNF439 ZNF581 ZNF587	6 interactors: CDH5 KRTAP5-9 MCM2 NOTCH2NL PIH1D3 WNT4
Entrez ID		3846	5025
HPRD ID		01008	09017
Ensembl ID		ENSG00000254997	ENSG00000135124
Uniprot IDs		P26371	E7EPF7 F6RU17 Q5U089 Q99571
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Keratinocyte Differentiation Pattern Specification Process Epidermal Cell Differentiation Developmental Process Positive Regulation Of Immune Response To Tumor Cell Adhesion Of Symbiont To Host Locomotion Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Muscle Hypertrophy Organ Development Cell Recognition Skin Development Multicellular Organismal Development Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Anterior/posterior Pattern Specification Cell Differentiation System Development Epidermis Development Transcription, DNA-templated	Immature T Cell Proliferation In Thymus Positive Regulation Of Cortisol Biosynthetic Process Negative Regulation Of Testicular Blood Vessel Morphogenesis Negative Regulation Of Testosterone Biosynthetic Process Negative Regulation Of Male Gonad Development Positive Regulation Of Aldosterone Biosynthetic Process Female Sex Determination Regulation Of Testosterone Biosynthetic Process Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Dermatome Development Thyroid-stimulating Hormone-secreting Cell Differentiation Renal Vesicle Induction Paramesonephric Duct Development Somatotropin Secreting Cell Differentiation Metanephric Mesenchymal Cell Differentiation Metanephric Tubule Formation Non-canonical Wnt Signaling Pathway Via MAPK Cascade Neuroendocrine Cell Differentiation Positive Regulation Of Steroid Hormone Biosynthetic Process Mesenchymal Cell Differentiation Involved In Kidney Development Mammary Gland Branching Involved In Pregnancy Renal Vesicle Formation Blood Vessel Maturation Regulation Of Glucocorticoid Biosynthetic Process Negative Regulation Of Hormone Biosynthetic Process DNA Unwinding Involved In DNA Replication Positive Regulation Of Hormone Biosynthetic Process Regulation Of Glucocorticoid Metabolic Process Cell Differentiation Involved In Metanephros Development Metanephric Tubule Morphogenesis Adenohypophysis Development Axonemal Dynein Complex Assembly Renal Vesicle Morphogenesis Androgen Biosynthetic Process Mesenchymal To Epithelial Transition Positive Regulation Of Meiotic Nuclear Division Metanephric Mesenchyme Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Steroid Metabolic Process Metanephric Nephron Morphogenesis Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Cellular Response To Epidermal Growth Factor Stimulus Sex Determination Regulation Of Hormone Biosynthetic Process Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Steroid Metabolic Process Positive Regulation Of Collagen Metabolic Process DNA Strand Elongation Involved In DNA Replication
Tagcloud ?			acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Difference) ?			acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Intersection) ?