KRTAP5-9 and TOMM22

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP5-9	TOMM22
Description		keratin associated protein 5-9	translocase of outer mitochondrial membrane 22
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane TOM Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding
	Biological Process	Epidermis Development	Protein Targeting To Mitochondrion Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix Protein Insertion Into Mitochondrial Outer Membrane
Pathways		Keratinization	Mitochondrial protein import PINK1-PRKN Mediated Mitophagy
Drugs
Diseases
GWAS			C-reactive protein levels ( 30388399) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		201 interacting genes: ABHD17A ADAM12 ADAMTSL4 ADAMTSL5 ALDH3B1 ALPP ATG9A BEX2 BMP7 BRME1 C10orf62 C11orf87 CATSPER1 CHIC2 CHRD CHRNG CKS1B CNNM3 COL8A1 COMT CRCT1 CREB5 CRH CRY2 CTNNBIP1 CTSZ CXCL16 CYSRT1 DCDC2 DHRS1 DMRT3 DNASE1L3 DOCK2 EMC7 ENKD1 ENPP7 FAH FAM124B FAM161A FAM74A4 FAM76B FLT3LG GGN GLP1R GLRX3 GNE GRN GSC2 HEY2 HHEX HLCS HOXA1 HOXB9 HPCAL1 HSD3B7 HSPD1 ICAM4 IGFBP6 JOSD1 KLHL38 KLK8 KPRP KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 LNX1 LY6H MAPKBP1 MEOX2 MOBP MT1M NAXD NBPF19 NCLN NECTIN2 NECTIN3 NKD1 NLK NMU NOTCH2NLA NPBWR2 NPDC1 NR4A3 NTAQ1 NTM NTN4 NUFIP2 OTX1 P2RX4 P2RY6 P4HB PCSK5 PDE9A PFKL PGAP6 PGLS PHLDA1 PIN1 POM121L8P POTEB3 POU4F2 PRKAB2 PSMA1 PTK7 PTPMT1 RAMP3 RASD1 RGS20 RNF111 SCARB1 SCNM1 SDC3 SDCBP SEMA3B SHFL SLC13A5 SLC15A3 SLC22A23 SLC25A10 SLC6A20 SMCP SPATA3 SPATC1L SPG7 SPINK2 SPRY1 SPRY2 TBC1D10C TBC1D16 TCEA2 TCEANC TGM1 TOMM22 TRARG1 TYRO3 UBE2I UXT VWC2 WNT11 YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF266 ZNF408 ZNF414 ZNF417 ZNF439 ZNF440 ZNF581 ZNF587 ZNF655 ZNF696 ZNF837	5 interacting genes: AQP6 HSD17B10 KRTAP5-9 TOMM20 TOMM7
Entrez ID		3846	56993
HPRD ID		01008	06130
Ensembl ID		ENSG00000254997	ENSG00000100216
Uniprot IDs		P26371	Q549C5 Q9NS69
PDB IDs			7CK6 7CP9 7VBY 7VC4 7VD2 7VDD 8XVA 9EIH 9EII 9EIJ
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Protein Binding Tissue Development Hair Cycle Axis Elongation	Mitochondrial Outer Membrane Translocase Complex TOM Complex Protein Insertion Into Mitochondrial Outer Membrane Protein Import Into Mitochondrial Matrix Protein Transmembrane Transporter Activity Mitochondrion Organization Establishment Of Protein Localization To Mitochondrial Membrane Protein Insertion Into Mitochondrial Membrane Protein Localization To Mitochondrion Protein Insertion Into Membrane Nitrate Transmembrane Transporter Activity Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity Cholate 7-alpha-dehydrogenase (NAD+) Activity Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Protein Transmembrane Transport Establishment Of Protein Localization To Mitochondrion Protein-transporting ATPase Activity Mitochondrial Membrane Organization PH-gated Chloride Channel Activity Nitrate Transmembrane Transport 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity Brexanolone Metabolic Process TRNA Import Into Mitochondrion Mitochondrial Ribonuclease P Complex Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing Mitochondrial TRNA Methylation Mitochondrial RNA 5'-end Processing Migrasome Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Isoleucine Metabolic Process L-isoleucine Catabolic Process RNA Import Into Mitochondrion Establishment Of Protein Localization To Membrane Mitochondrion Targeting Sequence Binding Mitochondrial Outer Membrane TRNA Methyltransferase Complex Mitochondrial RNA 3'-end Processing Testosterone Dehydrogenase (NAD+) Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity TRNA Transport Androstan-3-alpha,17-beta-diol Dehydrogenase (NAD+) Activity Monoatomic Anion Channel Activity Renal Water Transport TRNA 3'-end Processing Transmembrane Transport Ammonium Channel Activity
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