KRTAP5-9 and ICAM4

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRTAP5-9	ICAM4
Description		keratin associated protein 5-9	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Region Plasma Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Integrin Binding Protein Binding
	Biological Process	Epidermis Development	Cell Adhesion Cell-cell Adhesion
Pathways		Keratinization	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		201 interacting genes: ABHD17A ADAM12 ADAMTSL4 ADAMTSL5 ALDH3B1 ALPP ATG9A BEX2 BMP7 BRME1 C10orf62 C11orf87 CATSPER1 CHIC2 CHRD CHRNG CKS1B CNNM3 COL8A1 COMT CRCT1 CREB5 CRH CRY2 CTNNBIP1 CTSZ CXCL16 CYSRT1 DCDC2 DHRS1 DMRT3 DNASE1L3 DOCK2 EMC7 ENKD1 ENPP7 FAH FAM124B FAM161A FAM74A4 FAM76B FLT3LG GGN GLP1R GLRX3 GNE GRN GSC2 HEY2 HHEX HLCS HOXA1 HOXB9 HPCAL1 HSD3B7 HSPD1 ICAM4 IGFBP6 JOSD1 KLHL38 KLK8 KPRP KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 LNX1 LY6H MAPKBP1 MEOX2 MOBP MT1M NAXD NBPF19 NCLN NECTIN2 NECTIN3 NKD1 NLK NMU NOTCH2NLA NPBWR2 NPDC1 NR4A3 NTAQ1 NTM NTN4 NUFIP2 OTX1 P2RX4 P2RY6 P4HB PCSK5 PDE9A PFKL PGAP6 PGLS PHLDA1 PIN1 POM121L8P POTEB3 POU4F2 PRKAB2 PSMA1 PTK7 PTPMT1 RAMP3 RASD1 RGS20 RNF111 SCARB1 SCNM1 SDC3 SDCBP SEMA3B SHFL SLC13A5 SLC15A3 SLC22A23 SLC25A10 SLC6A20 SMCP SPATA3 SPATC1L SPG7 SPINK2 SPRY1 SPRY2 TBC1D10C TBC1D16 TCEA2 TCEANC TGM1 TOMM22 TRARG1 TYRO3 UBE2I UXT VWC2 WNT11 YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF266 ZNF408 ZNF414 ZNF417 ZNF439 ZNF440 ZNF581 ZNF587 ZNF655 ZNF696 ZNF837	14 interacting genes: CREB3 CYSRT1 ITGA4 ITGAM ITGAV ITGB1 ITGB2 KRT31 KRT34 KRTAP5-9 MTUS2 NBPF19 NOTCH2NLA RHAG
Entrez ID		3846	3386
HPRD ID		01008	00198
Ensembl ID		ENSG00000254997	ENSG00000105371
Uniprot IDs		P26371	Q14773 U5U6P8
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Protein Binding Tissue Development Hair Cycle Axis Elongation	Integrin Complex Heterotypic Cell-cell Adhesion C-X3-C Chemokine Binding Cell Adhesion Mediated By Integrin Integrin-mediated Signaling Pathway Cell-matrix Adhesion Integrin Binding Cell-substrate Adhesion Integrin AlphaM-beta2 Complex Integrin Alphav-beta1 Complex Fibronectin Binding Integrin Alpha4-beta1 Complex Positive Regulation Of Neutrophil Degranulation Endodermal Cell Differentiation Negative Regulation Of Dopamine Metabolic Process Epidermis Development Negative Regulation Of Catecholamine Metabolic Process Receptor-mediated Endocytosis Leukocyte Cell-cell Adhesion Cell-cell Adhesion Mediated By Integrin Regulation Of Neutrophil Degranulation Coreceptor Activity Tissue Development Endocytosis Complement Component C3b Binding Cell-cell Adhesion Specific Granule Membrane Negative Regulation Of Vasoconstriction Signaling Receptor Activity Cell Adhesion Molecule Binding Phagocytosis Wound Healing, Spreading Of Epidermal Cells Import Into Cell Leukocyte Tethering Or Rolling Regulation Of Dopamine Metabolic Process Positive Regulation Of Superoxide Anion Generation Regulation Of Superoxide Anion Generation Cell Surface Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell External Side Of Plasma Membrane Cellular Developmental Process Cargo Receptor Activity Positive Regulation Of Protein Targeting To Membrane Amyloid-beta Clearance Regulation Of Superoxide Metabolic Process Wound Healing, Spreading Of Cells Microglial Cell Activation Phagocytosis, Engulfment Cell Differentiation
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