NOTCH1 and CBL

  • Number of citations of the paper that reports this interaction (PMID 11777909)
  • 26
  • Data Source:
  • HPRD (in vivo)

NOTCH1

CBL

Gene Name notch 1 Cbl proto-oncogene, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 56 interactors: ADAM17 AKT1 APBA1 BLOC1S1 CACNA1A CAMK4 CBL CNTN1 CTNNB1 DLL1 DLL4 DTX1 DTX2 EGFL7 EP300 FBXW7 FURIN GFI1B GSK3B ILK ITCH JAG1 JAG2 KAT2A KAT2B LCK LEF1 LFNG MAML1 MAML2 MAML3 MDM2 MEF2C MFNG NFKB1 NOV NUMB NUMBL PIK3CG POFUT1 PSEN1 PSEN2 RBP3 RBPJ REL RELA RUNX3 SMAD3 SNAI1 SNW1 USP12 WDR12 WWP1 XIAP XRCC6 YY1 114 interactors: ABL1 ASAP1 AXL BCR BLK BLNK BTK CAPN1 CD19 CD2AP CD38 CD40 CD5 CDKL2 CRK CRKL CSF1R CTNNB1 CUBN EGFR EIF5B EPHA2 EPHB6 EPOR ERBB2 F2RL1 FGR FLOT1 FLT3 FNBP1 FRS2 FYB FYN GIF GRB2 HCK IGF1R INPPL1 INSR ITCH ITK ITSN2 KDR KHDRBS1 KIT KRT18 LAT LAT2 LCK LCP2 LRIG1 LTK LYN MAPK8 MET MYH9 MYO1C NCK1 NOTCH1 OSTF1 PDGFRA PDGFRB PIK3R1 PIK3R2 PLCG1 PRKCA PRKCQ PTK2B PTPN11 PTPN22 PTPN6 RET SCN5A SH2B2 SH3KBP1 SHC1 SLA SLA2 SORBS1 SORBS2 SPRY2 SRC STAP2 STAT5A STAT5B SYK TCN1 TCN2 TGFBR2 TNFRSF11A TNS4 TRAF4 TRAF6 TRIM8 TYK2 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2G2 UBE2L3 UBE2M USP21 VAV1 VAV2 YES1 YWHAB YWHAG YWHAQ YWHAZ ZAP70
Entrez ID 4851 867
HPRD ID 01827 01320
Ensembl ID ENSG00000148400 ENSG00000110395
Uniprot IDs P46531 P22681
PDB IDs 1PB5 1TOZ 1YYH 2F8X 2F8Y 2HE0 2VJ3 3ETO 3I08 3L95 3NBN 3V79 1B47 1FBV 1YVH 2CBL 2JUJ 2K4D 2OO9 2Y1M 2Y1N 3BUM 3BUN 3BUO 3BUW 3BUX 3OB1 3OB2 3PLF 4A49 4A4B 4A4C 4GPL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
a23187  alpha1  antitrypsin  biologically  carboxyl  cleaved  convertase  convertases  decisions  dibasic  digestion  disagree  exists  extend  fate  furin  heterodimeric  invertebrates  ionophore  lovo  nearby  pdx  processed  processing  proteolytic  rqrr  takes  vertebrates 
32dcl3  32p  antisera  eliminated  engagement  fusion  fyn  gst  hck  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
Tagcloud (Difference) ?
a23187  alpha1  antitrypsin  biologically  carboxyl  cleaved  convertase  convertases  decisions  dibasic  digestion  disagree  exists  extend  fate  furin  heterodimeric  invertebrates  ionophore  lovo  nearby  pdx  processed  processing  proteolytic  rqrr  takes  vertebrates 
32dcl3  32p  antisera  eliminated  engagement  fusion  fyn  gst  hck  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
Tagcloud (Intersection) ?