NOTCH1 and XIAP

  • Number of citations of the paper that reports this interaction (PMID 17318174)
  • 12
  • Data Source:
  • HPRD (in vitro, in vivo)

NOTCH1

XIAP

Gene Name notch 1 X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 56 interactors: ADAM17 AKT1 APBA1 BLOC1S1 CACNA1A CAMK4 CBL CNTN1 CTNNB1 DLL1 DLL4 DTX1 DTX2 EGFL7 EP300 FBXW7 FURIN GFI1B GSK3B ILK ITCH JAG1 JAG2 KAT2A KAT2B LCK LEF1 LFNG MAML1 MAML2 MAML3 MDM2 MEF2C MFNG NFKB1 NOV NUMB NUMBL PIK3CG POFUT1 PSEN1 PSEN2 RBP3 RBPJ REL RELA RUNX3 SMAD3 SNAI1 SNW1 USP12 WDR12 WWP1 XIAP XRCC6 YY1 67 interactors: ACVRL1 AFP AIFM1 AKT1 AKT2 BIRC5 BRCA1 CASP10 CASP3 CASP7 CASP9 CHEK1 CKS1B COMMD1 DIABLO DTX3 DYNLL2 ELAVL1 ERCC3 GSPT1 HTRA1 HTRA2 IKBKE INPP5D LONRF1 MAGED1 MAP3K2 MAP3K3 MAP3K7 NEK6 NOD1 NOD2 NOTCH1 RAF1 RFC5 RIPK1 RIPK2 RIPK3 RIPK4 SEPT4 SSX2IP STRADB STUB1 TAB1 TAB2 TBK1 TGFBR1 TRAF6 TRIM32 TRIM8 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2I UBE2J2 UBE2N UBE2V1 UBE2V2 UBE2W VPS37C WDYHV1 XAF1
Entrez ID 4851 331
HPRD ID 01827 02094
Ensembl ID ENSG00000148400 ENSG00000101966
Uniprot IDs P46531 B2R9R2 P98170
PDB IDs 1PB5 1TOZ 1YYH 2F8X 2F8Y 2HE0 2VJ3 3ETO 3I08 3L95 3NBN 3V79 1C9Q 1F9X 1G3F 1G73 1I3O 1I4O 1I51 1KMC 1NW9 1TFQ 1TFT 2ECG 2JK7 2KNA 2OPY 2OPZ 2POI 2POP 2QRA 2VSL 3CLX 3CM2 3CM7 3EYL 3G76 3HL5 3UW4 3UW5 4EC4 4HY0 4IC2 4IC3 4J3Y 4J44 4J45 4J46 4J47 4J48
Enriched GO Terms of Interacting Partners?
Tagcloud ?
a23187  alpha1  antitrypsin  biologically  carboxyl  cleaved  convertase  convertases  decisions  dibasic  digestion  disagree  exists  extend  fate  furin  heterodimeric  invertebrates  ionophore  lovo  nearby  pdx  processed  processing  proteolytic  rqrr  takes  vertebrates 
anthracyclines  antiapoptotic  apaf  bcp  carbinol  childhood  coadministration  cruciferous  cure  doxorubicin  dramatic  evidenced  i3c  iap1  indole  innovative  lymphoblastic  modality  nalm  nontoxic  noxa  opportunities  parp  phytochemical  potentiates  puma  topoisomerase  vegetables  xl 
Tagcloud (Difference) ?
a23187  alpha1  antitrypsin  biologically  carboxyl  cleaved  convertase  convertases  decisions  dibasic  digestion  disagree  exists  extend  fate  furin  heterodimeric  invertebrates  ionophore  lovo  nearby  pdx  processed  processing  proteolytic  rqrr  takes  vertebrates 
anthracyclines  antiapoptotic  apaf  bcp  carbinol  childhood  coadministration  cruciferous  cure  doxorubicin  dramatic  evidenced  i3c  iap1  indole  innovative  lymphoblastic  modality  nalm  nontoxic  noxa  opportunities  parp  phytochemical  potentiates  puma  topoisomerase  vegetables  xl 
Tagcloud (Intersection) ?