NOTCH1 and LEF1

  • Number of citations of the paper that reports this interaction (PMID 11604490)
  • 29
  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vivo, in vitro)

NOTCH1

LEF1

Gene Name notch 1 lymphoid enhancer-binding factor 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 56 interactors: ADAM17 AKT1 APBA1 BLOC1S1 CACNA1A CAMK4 CBL CNTN1 CTNNB1 DLL1 DLL4 DTX1 DTX2 EGFL7 EP300 FBXW7 FURIN GFI1B GSK3B ILK ITCH JAG1 JAG2 KAT2A KAT2B LCK LEF1 LFNG MAML1 MAML2 MAML3 MDM2 MEF2C MFNG NFKB1 NOV NUMB NUMBL PIK3CG POFUT1 PSEN1 PSEN2 RBP3 RBPJ REL RELA RUNX3 SMAD3 SNAI1 SNW1 USP12 WDR12 WWP1 XIAP XRCC6 YY1 28 interactors: ALX4 ALYREF CDX1 CTNNB1 DPYSL2 EP300 KPNA1 KPNA2 MITF NARF NLK NOTCH1 PIAS4 PITX2 RNF138 RUNX2 SETD8 SMAD1 SMAD2 SMAD3 SMAD4 STAT5A SUMO2 TLE1 TLE2 TRA UBTF ZBTB3
Entrez ID 4851 51176
HPRD ID 01827 01075
Ensembl ID ENSG00000148400 ENSG00000138795
Uniprot IDs P46531 Q659G9 Q9UJU2
PDB IDs 1PB5 1TOZ 1YYH 2F8X 2F8Y 2HE0 2VJ3 3ETO 3I08 3L95 3NBN 3V79
Enriched GO Terms of Interacting Partners?
Tagcloud ?
a23187  alpha1  antitrypsin  biologically  carboxyl  cleaved  convertase  convertases  decisions  dibasic  digestion  disagree  exists  extend  fate  furin  heterodimeric  invertebrates  ionophore  lovo  nearby  pdx  processed  processing  proteolytic  rqrr  takes  vertebrates 
abolishes  accumulations  allowing  bulge  collectively  constitutes  disrupted  drives  follicle  gatekeeper  give  hair  heterogeneity  initiating  interferes  intriguingly  mechanistically  mimics  normally  plasticity  propagation  protecting  rise  sc  scs  sebaceous  tumour  tumours  uncontrolled 
Tagcloud (Difference) ?
a23187  alpha1  antitrypsin  biologically  carboxyl  cleaved  convertase  convertases  decisions  dibasic  digestion  disagree  exists  extend  fate  furin  heterodimeric  invertebrates  ionophore  lovo  nearby  pdx  processed  processing  proteolytic  rqrr  takes  vertebrates 
abolishes  accumulations  allowing  bulge  collectively  constitutes  disrupted  drives  follicle  gatekeeper  give  hair  heterogeneity  initiating  interferes  intriguingly  mechanistically  mimics  normally  plasticity  propagation  protecting  rise  sc  scs  sebaceous  tumour  tumours  uncontrolled 
Tagcloud (Intersection) ?