LYN and INPP5D

  • Number of citations of the paper that reports this interaction (PMID 12882960)
  • 19
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)
  • HPRD (in vivo, in vitro)

LYN

INPP5D

Gene Name LYN proto-oncogene, Src family tyrosine kinase inositol polyphosphate-5-phosphatase, 145kDa
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 115 interactors: ACTB ADAM15 BANK1 BCAR1 BTK CASP3 CASP7 CASP9 CBL CBLC CD19 CD22 CD36 CD72 CD79A CD79B CDK1 CDK2 CDKN1B CHST15 CREBBP CRKL CSF1R CSF2RA CSF2RB CSF3R CSK CSNK2B CTLA4 DAPP1 DLG4 DOK1 DOK2 DOK3 EGFR EPOR EVL FASLG FCAR FCER1G FCGR2A FCGR2B FOLR1 GAB2 GAB3 GP6 GRIA3 HCLS1 HNRNPK IL1B IL2RB IL7R INPP5D ITPR1 JAK2 KHDRBS1 KIT LCP2 LIME1 MAP4K1 MAPK3 MATK MME MS4A1 MS4A2 MUC1 NDFIP2 NEDD9 NMT1 NPHS1 PAG1 PAK2 PDE4A PDE4D PECAM1 PIK3CG PILRB PLCG1 PLCG2 PPP1R15A PPP1R8 PRAM1 PRKCD PRKCQ PRKDC PTK2 PTK2B PTPN6 PTPRC RASA1 RGS16 RPL10 RPS6KB1 RPS6KB2 SH2B2 SHC1 SKAP1 SKAP2 SLC4A1 SNCA SPHK1 SPHK2 SRC STAT3 SYK TEC TNF TRAT1 TRIM28 TRIP10 TRPV4 TYK2 UBB UHRF2 UNC119 40 interactors: ARAP1 CD22 CD300LF CRKL CSF1R CSF3R DAB1 DAB2 DOK1 DOK2 DOK3 EPOR FCGR2B FGR FLT3 GAB1 GAB2 GRB2 HCK IL4R JAK1 JAK3 KHDRBS3 KIT KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 LILRB4 LYN MET NOTCH2NL PECAM1 PLCG1 PTPN11 SH3KBP1 SHC1 XIAP ZDHHC17
Entrez ID 4067 3635
HPRD ID 01301 09033
Ensembl ID ENSG00000254087 ENSG00000168918
Uniprot IDs A8K379 P07948 Q6NUK7 Q92835
PDB IDs 1W1F 1WA7 3A4O 2YSX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
cytoskeleton  dataset  deposited  dysregulation  exerts  expand  heterodimeric  http  identifier  inositol  mapkapk2  nad  nadk  nonreceptor  org  pertaining  phosphatases  phosphoproteome  phosphoproteomic  polyphosphate  proteomecentral  proteomexchange  ptpn12  pxd000984  reorganization  ripk1  silac  threonine  tnfrsf 
Tagcloud (Difference) ?
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
cytoskeleton  dataset  deposited  dysregulation  exerts  expand  heterodimeric  http  identifier  inositol  mapkapk2  nad  nadk  nonreceptor  org  pertaining  phosphatases  phosphoproteome  phosphoproteomic  polyphosphate  proteomecentral  proteomexchange  ptpn12  pxd000984  reorganization  ripk1  silac  threonine  tnfrsf 
Tagcloud (Intersection) ?