LYN and IL2RB

  • Number of citations of the paper that reports this interaction (PMID 1557373)
  • 16
  • Data Source:
  • HPRD (in vivo, in vitro)

LYN

IL2RB

Gene Name LYN proto-oncogene, Src family tyrosine kinase interleukin 2 receptor, beta
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 115 interactors: ACTB ADAM15 BANK1 BCAR1 BTK CASP3 CASP7 CASP9 CBL CBLC CD19 CD22 CD36 CD72 CD79A CD79B CDK1 CDK2 CDKN1B CHST15 CREBBP CRKL CSF1R CSF2RA CSF2RB CSF3R CSK CSNK2B CTLA4 DAPP1 DLG4 DOK1 DOK2 DOK3 EGFR EPOR EVL FASLG FCAR FCER1G FCGR2A FCGR2B FOLR1 GAB2 GAB3 GP6 GRIA3 HCLS1 HNRNPK IL1B IL2RB IL7R INPP5D ITPR1 JAK2 KHDRBS1 KIT LCP2 LIME1 MAP4K1 MAPK3 MATK MME MS4A1 MS4A2 MUC1 NDFIP2 NEDD9 NMT1 NPHS1 PAG1 PAK2 PDE4A PDE4D PECAM1 PIK3CG PILRB PLCG1 PLCG2 PPP1R15A PPP1R8 PRAM1 PRKCD PRKCQ PRKDC PTK2 PTK2B PTPN6 PTPRC RASA1 RGS16 RPL10 RPS6KB1 RPS6KB2 SH2B2 SHC1 SKAP1 SKAP2 SLC4A1 SNCA SPHK1 SPHK2 SRC STAT3 SYK TEC TNF TRAT1 TRIM28 TRIP10 TRPV4 TYK2 UBB UHRF2 UNC119 27 interactors: CISH EIF3B FYN GNB2L1 GRB2 HGS IL15 IL15RA IL2 IL2RA IL2RG JAK1 JAK3 LCK LYN PIK3R1 PTPN6 RAF1 SHB SHC1 SOCS1 SOCS3 STAT1 STAT3 STAT5A STAT5B SYK
Entrez ID 4067 3560
HPRD ID 01301 00896
Ensembl ID ENSG00000254087 ENSG00000100385
Uniprot IDs A8K379 P07948 Q6NUK7 P14784
PDB IDs 1W1F 1WA7 3A4O 1ILM 1ILN 2B5I 2ERJ 3QAZ 4GS7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
attenuation  autocrine  coculture  coexpression  conundrum  defining  engagement  explanation  favorable  heterotrimer  il15  il15ra  il2rg  infiltrations  jak1  leucocyte  mechanistic  offer  overexpress  paracrine  paradoxical  pras40  rnai  stat2  stroma  subsets  tnbc  unlike 
Tagcloud (Difference) ?
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
attenuation  autocrine  coculture  coexpression  conundrum  defining  engagement  explanation  favorable  heterotrimer  il15  il15ra  il2rg  infiltrations  jak1  leucocyte  mechanistic  offer  overexpress  paracrine  paradoxical  pras40  rnai  stat2  stroma  subsets  tnbc  unlike 
Tagcloud (Intersection) ?