LYN and DOK1

  • Number of citations of the paper that reports this interaction (PMID 11071635)
  • 19
  • Data Source:
  • HPRD (in vitro, in vivo)

LYN

DOK1

Gene Name LYN proto-oncogene, Src family tyrosine kinase docking protein 1, 62kDa (downstream of tyrosine kinase 1)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 115 interactors: ACTB ADAM15 BANK1 BCAR1 BTK CASP3 CASP7 CASP9 CBL CBLC CD19 CD22 CD36 CD72 CD79A CD79B CDK1 CDK2 CDKN1B CHST15 CREBBP CRKL CSF1R CSF2RA CSF2RB CSF3R CSK CSNK2B CTLA4 DAPP1 DLG4 DOK1 DOK2 DOK3 EGFR EPOR EVL FASLG FCAR FCER1G FCGR2A FCGR2B FOLR1 GAB2 GAB3 GP6 GRIA3 HCLS1 HNRNPK IL1B IL2RB IL7R INPP5D ITPR1 JAK2 KHDRBS1 KIT LCP2 LIME1 MAP4K1 MAPK3 MATK MME MS4A1 MS4A2 MUC1 NDFIP2 NEDD9 NMT1 NPHS1 PAG1 PAK2 PDE4A PDE4D PECAM1 PIK3CG PILRB PLCG1 PLCG2 PPP1R15A PPP1R8 PRAM1 PRKCD PRKCQ PRKDC PTK2 PTK2B PTPN6 PTPRC RASA1 RGS16 RPL10 RPS6KB1 RPS6KB2 SH2B2 SHC1 SKAP1 SKAP2 SLC4A1 SNCA SPHK1 SPHK2 SRC STAT3 SYK TEC TNF TRAT1 TRIM28 TRIP10 TRPV4 TYK2 UBB UHRF2 UNC119 39 interactors: ABL1 ABL2 BCR CRK CRKL CSK ERBB2 FES FGR FYN GRB10 HCK INPP5D INSR ITGB1 ITGB2 ITGB3 ITGB5 ITGB7 ITK KIT LCK LYN MAP4K4 NCK1 NCK2 PIK3R1 PLCG1 PTK6 PTPN6 PTPRH RASA1 RET SH2D1A SHC1 SRC TEC VAV1 YES1
Entrez ID 4067 1796
HPRD ID 01301 04228
Ensembl ID ENSG00000254087 ENSG00000115325
Uniprot IDs A8K379 P07948 Q6NUK7 B3KP83 B4DJN1 Q2TA81 Q99704
PDB IDs 1W1F 1WA7 3A4O 2V76
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
adaptors  coimmunoprecipitated  comprises  epcs  epo  epor  erythroblast  erythroblasts  gab1  hemoglobinizing  homo  irs2  orf  phosphoproteomics  phosphotyrosine  primates  propagates  py  rhex  sapiens  sh2d2a  shc1  sprouty  spry1  spry2  stam2  transducing  ut7epo  validating 
Tagcloud (Difference) ?
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
adaptors  coimmunoprecipitated  comprises  epcs  epo  epor  erythroblast  erythroblasts  gab1  hemoglobinizing  homo  irs2  orf  phosphoproteomics  phosphotyrosine  primates  propagates  py  rhex  sapiens  sh2d2a  shc1  sprouty  spry1  spry2  stam2  transducing  ut7epo  validating 
Tagcloud (Intersection) ?