LYN and CDK2

  • Number of citations of the paper that reports this interaction (PMID 8806683)
  • 5
  • Data Source:
  • HPRD (in vivo, in vitro)

LYN

CDK2

Gene Name LYN proto-oncogene, Src family tyrosine kinase cyclin-dependent kinase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 115 interactors: ACTB ADAM15 BANK1 BCAR1 BTK CASP3 CASP7 CASP9 CBL CBLC CD19 CD22 CD36 CD72 CD79A CD79B CDK1 CDK2 CDKN1B CHST15 CREBBP CRKL CSF1R CSF2RA CSF2RB CSF3R CSK CSNK2B CTLA4 DAPP1 DLG4 DOK1 DOK2 DOK3 EGFR EPOR EVL FASLG FCAR FCER1G FCGR2A FCGR2B FOLR1 GAB2 GAB3 GP6 GRIA3 HCLS1 HNRNPK IL1B IL2RB IL7R INPP5D ITPR1 JAK2 KHDRBS1 KIT LCP2 LIME1 MAP4K1 MAPK3 MATK MME MS4A1 MS4A2 MUC1 NDFIP2 NEDD9 NMT1 NPHS1 PAG1 PAK2 PDE4A PDE4D PECAM1 PIK3CG PILRB PLCG1 PLCG2 PPP1R15A PPP1R8 PRAM1 PRKCD PRKCQ PRKDC PTK2 PTK2B PTPN6 PTPRC RASA1 RGS16 RPL10 RPS6KB1 RPS6KB2 SH2B2 SHC1 SKAP1 SKAP2 SLC4A1 SNCA SPHK1 SPHK2 SRC STAT3 SYK TEC TNF TRAT1 TRIM28 TRIP10 TRPV4 TYK2 UBB UHRF2 UNC119 120 interactors: ACKR4 ACTL6A ARID4A BCL2 BRCA1 BRCA2 BTBD2 C12orf65 CCNA1 CCNA2 CCNB2 CCNB3 CCNE1 CCNE2 CCNH CCNK CCP110 CDC25A CDC25B CDC25C CDC37 CDC5L CDC6 CDC7 CDK20 CDK2AP1 CDK7 CDKN1A CDKN1B CDKN3 CDT1 CDX2 CEBPA CHAF1A CHAF1B CKS1B CKS2 CNOT7 COIL CTNNB1 DBF4 E2F1 EP300 ESR1 EZH2 FEN1 FOXM1 FZR1 H1F0 HIRA HIST1H1A HIST1H1B HIST1H1D HIST1H2AB HIST1H2BB HIST1H4A ID2 ID3 IKBKG IL15RA INCA1 KAT2A KAT2B KIF26B LATS2 LYN MAPRE2 MAPT MARCKS MCM2 MCM3 MCM4 MNDA MYBL2 MYOD1 NFYA NPDC1 NPM1 ORC1 ORC2 PCNA PGR PHLDA3 PIN1 PML POLA1 POLD1 POLD2 POLL PPM1B PPP2CA PRC1 PRKAR1A PRKCH PTHLH PTMA PTPN2 RB1 RBL1 RBL2 RBM4 RPA1 RRN3 SCN5A SKP1 SKP2 SMAD2 SMAD3 SP1 SPDYA TFDP1 TP53 TP73 TSPYL2 TTK UBE2A UBTF UHRF2 WEE1 XRCC6
Entrez ID 4067 1017
HPRD ID 01301 00310
Ensembl ID ENSG00000254087 ENSG00000123374
Uniprot IDs A8K379 P07948 Q6NUK7 E7ESI2 P24941
PDB IDs 1W1F 1WA7 3A4O 1AQ1 1B38 1B39 1BUH 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1F5Q 1FIN 1FQ1 1FVT 1FVV 1G5S 1GIH 1GII 1GIJ 1GY3 1GZ8 1H00 1H01 1H07 1H08 1H0V 1H0W 1H1P 1H1Q 1H1R 1H1S 1H24 1H25 1H26 1H27 1H28 1HCK 1HCL 1JST 1JSU 1JSV 1JVP 1KE5 1KE6 1KE7 1KE8 1KE9 1OGU 1OI9 1OIQ 1OIR 1OIT 1OIU 1OIY 1OKV 1OKW 1OL1 1OL2 1P2A 1P5E 1PF8 1PKD 1PW2 1PXI 1PXJ 1PXK 1PXL 1PXM 1PXN 1PXO 1PXP 1PYE 1QMZ 1R78 1URC 1URW 1V1K 1VYW 1VYZ 1W0X 1W8C 1W98 1WCC 1Y8Y 1Y91 1YKR 2A0C 2A4L 2B52 2B53 2B54 2B55 2BHE 2BHH 2BKZ 2BPM 2BTR 2BTS 2C4G 2C5N 2C5O 2C5V 2C5X 2C5Y 2C68 2C69 2C6I 2C6K 2C6L 2C6M 2C6O 2C6T 2CCH 2CCI 2CJM 2CLX 2DS1 2DUV 2EXM 2FVD 2G9X 2HIC 2I40 2IW6 2IW8 2IW9 2J9M 2JGZ 2R3F 2R3G 2R3H 2R3I 2R3J 2R3K 2R3L 2R3M 2R3N 2R3O 2R3P 2R3Q 2R3R 2R64 2UUE 2UZB 2UZD 2UZE 2UZL 2UZN 2UZO 2V0D 2V22 2VTA 2VTH 2VTI 2VTJ 2VTL 2VTM 2VTN 2VTO 2VTP 2VTQ 2VTR 2VTS 2VTT 2VU3 2VV9 2W05 2W06 2W17 2W1H 2WEV 2WFY 2WHB 2WIH 2WIP 2WMA 2WMB 2WPA 2WXV 2X1N 2XMY 2XNB 3BHT 3BHU 3BHV 3DDP 3DDQ 3DOG 3EID 3EJ1 3EOC 3EZR 3EZV 3F5X 3FZ1 3IG7 3IGG 3LE6 3LFN 3LFQ 3LFS 3MY5 3NS9 3PJ8 3PXF 3PXQ 3PXR 3PXY 3PXZ 3PY0 3PY1 3QHR 3QHW 3QL8 3QQF 3QQG 3QQH 3QQJ 3QQK 3QQL 3QRT 3QRU 3QTQ 3QTR 3QTS 3QTU 3QTW 3QTX 3QTZ 3QU0 3QWJ 3QWK 3QX2 3QX4 3QXO 3QXP 3QZF 3QZG 3QZH 3QZI 3R1Q 3R1S 3R1Y 3R28 3R6X 3R71 3R73 3R7E 3R7I 3R7U 3R7V 3R7Y 3R83 3R8L 3R8M 3R8P 3R8U 3R8V 3R8Z 3R9D 3R9H 3R9N 3R9O 3RAH 3RAI 3RAK 3RAL 3RJC 3RK5 3RK7 3RK9 3RKB 3RM6 3RM7 3RMF 3RNI 3ROY 3RPO 3RPR 3RPV 3RPY 3RZB 3S00 3S0O 3S1H 3S2P 3SQQ 3SW4 3SW7 3TI1 3TIY 3TIZ 3TNW 3ULI 3UNJ 3UNK 4ACM 4BCK 4BCM 4BCN 4BCO 4BCP 4BCQ 4BGH 4EK3 4EK4 4EK5 4EK6 4EK8 4EOI 4EOJ 4EOK 4EOL 4EOM 4EON 4EOO 4EOP 4EOQ 4EOR 4EOS 4ERW 4EZ3 4EZ7 4FKG 4FKI 4FKJ 4FKL 4FKO 4FKP 4FKQ 4FKR 4FKS 4FKT 4FKU 4FKV 4FKW 4FX3 4GCJ 4I3Z 4II5 4KD1 4LYN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
adenovirus  alleviates  altogether  arrest  arrested  besides  bypasses  bypassing  cyclins  d3  delta26  e1a  e2f  fails  imply  ink4a  kip1  oncoprotein  owing  p16  p27  prb  prevents  restore  retinoblastoma  rodent  roscovitine  supraphysiological 
Tagcloud (Difference) ?
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
adenovirus  alleviates  altogether  arrest  arrested  besides  bypasses  bypassing  cyclins  d3  delta26  e1a  e2f  fails  imply  ink4a  kip1  oncoprotein  owing  p16  p27  prb  prevents  restore  retinoblastoma  rodent  roscovitine  supraphysiological 
Tagcloud (Intersection) ?