LDHA and ACD

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		LDHA	ACD
Gene Name		lactate dehydrogenase A	adrenocortical dysplasia homolog (mouse)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Membrane Sperm Fibrous Sheath Extracellular Vesicular Exosome	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm
	Molecular Function	L-lactate Dehydrogenase Activity Protein Binding	DNA Binding Protein Binding DNA Polymerase Binding
	Biological Process	Pyruvate Metabolic Process Glycolytic Process Substantia Nigra Development Cellular Response To Extracellular Stimulus Cellular Metabolic Process Cellular Carbohydrate Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Segmentation Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region
Pathways		Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport	Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs		NADH Nicotinamide-Adenine-Dinucleotide Etheno-Nad Nicotinamide Oxamic Acid
Diseases
GWAS		Amyloid A Levels ( 21124955)
Protein-Protein Interactions		15 interactors: ABCC9 ACD DYNLL1 HNRNPD KCNJ11 LDHB MAPK10 NDRG1 PCNA POT1 TERF1 TINF2 UPF2 XRN1 YWHAQ	59 interactors: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790
Entrez ID		3939	65057
HPRD ID		01025	12417
Ensembl ID		ENSG00000134333	ENSG00000102977
Uniprot IDs		P00338	Q96AP0
PDB IDs		1I10 4AJP 4JNK 4M49	2I46
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Maintenance Telomere Assembly Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Replication Negative Regulation Of DNA Replication Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of DNA Biosynthetic Process Positive Regulation Of Organelle Organization Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Regulation Of Chromosome Organization Regulation Of Organelle Organization Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA-dependent DNA Replication Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Potassium Ion Import Homeostatic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Protein Localization To Chromosome Cellular Nitrogen Compound Metabolic Process RNA Catabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Substantia Nigra Development Chromosome Organization DNA Metabolic Process Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Neural Nucleus Development Cell Cycle Phase Transition Positive Regulation Of Mitochondrion Organization DNA Replication Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Deoxyribonuclease Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation	Organelle Organization Protein Folding Carbohydrate Catabolic Process Substantia Nigra Development Neural Nucleus Development 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Nervous System Development Catabolic Process Cellular Component Assembly Midbrain Development Glycolytic Process Multicellular Organismal Development Negative Regulation Of Telomere Maintenance Via Telomerase Generation Of Neurons Telomere Assembly Pyruvate Metabolic Process Neurogenesis Developmental Process Negative Regulation Of Telomere Maintenance Monosaccharide Metabolic Process Regulation Of Cellular Protein Metabolic Process Brain Development Cellular Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Head Development Glucose Metabolic Process Neuron Projection Development Neuron Projection Morphogenesis Telomere Maintenance Cell Differentiation Neuron Differentiation Regulation Of Protein Metabolic Process System Development DNA Duplex Unwinding DNA Geometric Change Regulation Of Telomere Maintenance Cellular Process Neuron Development Adherens Junction Organization Central Nervous System Development Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Negative Regulation Of DNA Metabolic Process Protein Polymerization Regulation Of Signaling Innate Immune Response DNA Metabolic Process
Tagcloud ?		11p 11q assignment cat chromosomes ets1 hbb homologous homology hras1 hsa hybrids ins karyotype karyotypes karyotypically loci monkey owl panels portion primate pth rodent segregation shared syntenic thy1 vi	acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86
Tagcloud (Difference) ?		11p 11q assignment cat chromosomes ets1 hbb homologous homology hras1 hsa hybrids ins karyotype karyotypes karyotypically loci monkey owl panels portion primate pth rodent segregation shared syntenic thy1 vi	acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86
Tagcloud (Intersection) ?