ACD and LLGL1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ACD	LLGL1
Gene Name		adrenocortical dysplasia homolog (mouse)	lethal giant larvae homolog 1 (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm	Golgi Cis Cisterna Golgi Membrane Cytoplasm Cytoskeleton Axon Cortical Actin Cytoskeleton Early Endosome Membrane Trans-Golgi Network Membrane Myelin Sheath Abaxonal Region
	Molecular Function	DNA Binding Protein Binding DNA Polymerase Binding	Rab GTPase Activator Activity Structural Molecule Activity Protein Binding Protein Kinase Binding
	Biological Process	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Segmentation Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region	Protein Complex Assembly Exocytosis Golgi To Plasma Membrane Transport Axonogenesis Cortical Actin Cytoskeleton Organization Positive Regulation Of Rab GTPase Activity Maintenance Of Apical/basal Cell Polarity
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS
Protein-Protein Interactions		59 interactors: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	4 interactors: ACD CACNA1A CD46 STX4
Entrez ID		65057	3996
HPRD ID		12417	02982
Ensembl ID		ENSG00000102977	ENSG00000131899
Uniprot IDs		Q96AP0	Q15334
PDB IDs		2I46
Enriched GO Terms of Interacting Partners?		Organelle Organization Protein Folding Carbohydrate Catabolic Process Substantia Nigra Development Neural Nucleus Development 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Nervous System Development Catabolic Process Cellular Component Assembly Midbrain Development Glycolytic Process Multicellular Organismal Development Negative Regulation Of Telomere Maintenance Via Telomerase Generation Of Neurons Telomere Assembly Pyruvate Metabolic Process Neurogenesis Developmental Process Negative Regulation Of Telomere Maintenance Monosaccharide Metabolic Process Regulation Of Cellular Protein Metabolic Process Brain Development Cellular Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Head Development Glucose Metabolic Process Neuron Projection Development Neuron Projection Morphogenesis Telomere Maintenance Cell Differentiation Neuron Differentiation Regulation Of Protein Metabolic Process System Development DNA Duplex Unwinding DNA Geometric Change Regulation Of Telomere Maintenance Cellular Process Neuron Development Adherens Junction Organization Central Nervous System Development Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Negative Regulation Of DNA Metabolic Process Protein Polymerization Regulation Of Signaling Innate Immune Response DNA Metabolic Process	Neurotransmitter Secretion Positive Regulation Of Single-stranded Telomeric DNA Binding Cerebellar Molecular Layer Development Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Vestibular Nucleus Development Positive Regulation Of Eosinophil Degranulation Regulation Of Insulin Secretion Response To Stress Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Regulation Of Peptide Hormone Secretion Gamma-aminobutyric Acid Secretion Regulation Of Hormone Secretion Cellular Protein Localization Interleukin-10 Production Regulation Of Acetylcholine Secretion, Neurotransmission Telomere Assembly Protection From Non-homologous End Joining At Telomere Positive Regulation Of Regulatory T Cell Differentiation Telomere Capping Rhythmic Synaptic Transmission Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Memory T Cell Differentiation Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cell Activation Regulation Of Synaptic Transmission Positive Regulation Of Telomerase Activity Exocytosis Positive Regulation Of Protein Localization To Cell Surface Sequestering Of Extracellular Ligand From Receptor Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Positive Regulation Of Immunoglobulin Secretion Positive Regulation Of Cell Adhesion Regulation Of Vesicle-mediated Transport Gamma-aminobutyric Acid Transport Regulation Of Memory T Cell Differentiation Chloride Ion Homeostasis Regulation Of Protein Secretion Negative Regulation Of Telomere Maintenance SNARE Complex Assembly Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Hormone Biosynthetic Process Regulation Of Telomere Maintenance Via Telomerase Pons Development Cellular Component Assembly Protein Localization Regulation Of Cellular Component Organization
Tagcloud ?		acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86	apical blastocyst cdx2 compaction dampened derives erm gtpases hippo icm lats1 lineages nanog outer pard6b phosphorylating polarity polarization prkcz rho rock scrib segregation specification specifying te trophectoderm tyrosinated yap
Tagcloud (Difference) ?		acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86	apical blastocyst cdx2 compaction dampened derives erm gtpases hippo icm lats1 lineages nanog outer pard6b phosphorylating polarity polarization prkcz rho rock scrib segregation specification specifying te trophectoderm tyrosinated yap
Tagcloud (Intersection) ?