ACD and ZFP36L1

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		ACD	ZFP36L1
Gene Name		adrenocortical dysplasia homolog (mouse)	ZFP36 ring finger protein-like 1
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm	Nucleus Cytosol
	Molecular Function	DNA Binding Protein Binding DNA Polymerase Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity MRNA Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Segmentation Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Vasculogenesis Proepicardium Development Regulation Of Transcription, DNA-templated Regulation Of Translation Apoptotic Process Heart Development Cell Proliferation Gene Expression Neural Tube Development T Cell Differentiation In Thymus Multicellular Organism Growth Regulation Of MRNA Stability Chorio-allantoic Fusion Spongiotrophoblast Layer Development
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis	Regulation of mRNA stability by proteins that bind AU-rich elements Butyrate Response Factor 1 (BRF1) destabilizes mRNA
Drugs
Diseases
GWAS			Celiac disease ( 20190752) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088) Prostate cancer ( 23535732)
Protein-Protein Interactions		59 interactors: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	9 interactors: ACD AKT1 MAPK14 MAPKAPK2 PAFAH1B2 POT1 TERF1 TINF2 YWHAB
Entrez ID		65057	677
HPRD ID		12417	03041
Ensembl ID		ENSG00000102977	ENSG00000185650
Uniprot IDs		Q96AP0	B3KNA8 Q07352
PDB IDs		2I46	1W0V 1W0W
Enriched GO Terms of Interacting Partners?		Organelle Organization Protein Folding Carbohydrate Catabolic Process Substantia Nigra Development Neural Nucleus Development 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Nervous System Development Catabolic Process Cellular Component Assembly Midbrain Development Glycolytic Process Multicellular Organismal Development Negative Regulation Of Telomere Maintenance Via Telomerase Generation Of Neurons Telomere Assembly Pyruvate Metabolic Process Neurogenesis Developmental Process Negative Regulation Of Telomere Maintenance Monosaccharide Metabolic Process Regulation Of Cellular Protein Metabolic Process Brain Development Cellular Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Head Development Glucose Metabolic Process Neuron Projection Development Neuron Projection Morphogenesis Telomere Maintenance Cell Differentiation Neuron Differentiation Regulation Of Protein Metabolic Process System Development DNA Duplex Unwinding DNA Geometric Change Regulation Of Telomere Maintenance Cellular Process Neuron Development Adherens Junction Organization Central Nervous System Development Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Negative Regulation Of DNA Metabolic Process Protein Polymerization Regulation Of Signaling Innate Immune Response DNA Metabolic Process	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Replication Telomere Maintenance Positive Regulation Of Transferase Activity Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of DNA Replication Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Organelle Organization Telomere Maintenance Via Telomere Lengthening Regulation Of Organelle Organization Regulation Of DNA Biosynthetic Process Regulation Of Chromosome Organization Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cellular Component Organization Neurotrophin Signaling Pathway Positive Regulation Of Metabolic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity 3'-UTR-mediated MRNA Stabilization Positive Regulation Of Telomere Maintenance Peptidyl-serine Phosphorylation Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of DNA Metabolic Process Positive Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Negative Regulation Of DNA Biosynthetic Process Cellular Response To Growth Factor Stimulus Regulation Of Protein Metabolic Process MRNA Stabilization Response To Growth Factor Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of MAPK Cascade
Tagcloud ?		acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86	antisense ccr4 deadenylase destabilization detailed disruption dissociation erk identifying ldlr lipoprotein oligonucleotide oligonucleotides p90 possibly potency proteomic recruit ribosomal rnas s6 stabilization stabilized therapeutics unstable untranslated usefulness utr
Tagcloud (Difference) ?		acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86	antisense ccr4 deadenylase destabilization detailed disruption dissociation erk identifying ldlr lipoprotein oligonucleotide oligonucleotides p90 possibly potency proteomic recruit ribosomal rnas s6 stabilization stabilized therapeutics unstable untranslated usefulness utr
Tagcloud (Intersection) ?