LDHA

Description		lactate dehydrogenase A
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Sperm Fibrous Sheath Extracellular Exosome Oxidoreductase Complex
	Molecular Function	Catalytic Activity Lactate Dehydrogenase Activity L-lactate Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Identical Protein Binding Cadherin Binding
	Biological Process	Lactate Metabolic Process Glycolytic Process Glucose Catabolic Process To Lactate Via Pyruvate Carboxylic Acid Metabolic Process Substantia Nigra Development Pyruvate Catabolic Process
Pathways		Pyruvate metabolism Regulation of pyruvate metabolism
Drugs		NADH Etheno-NAD Nicotinamide Oxamic Acid Stiripentol Copper Artenimol
Diseases
GWAS		Amyloid A serum levels ( 21124955) Serum metabolite levels ( 33031748)
Interacting Genes		21 interacting genes: ABCC9 ACD CEBPA DUX4 DYNLL1 FGFR1 GSK3A HNRNPD HULC KCNJ11 MAPK10 NDRG1 PCNA POT1 PTPRF SRPK2 TERF1 TINF2 UPF2 XRN1 YWHAQ
Entrez ID		3939
HPRD ID		01025
Ensembl ID		ENSG00000134333
Uniprot IDs		P00338 V9HWB9
PDB IDs		1I10 4AJP 4JNK 4L4R 4L4S 4M49 4OJN 4OKN 4QO7 4QO8 4QSM 4QT0 4R68 4R69 4RLS 4ZVV 5IXS 5IXY 5W8H 5W8I 5W8J 5W8K 5W8L 5ZJD 5ZJE 5ZJF 6BAD 6BAG 6BAX 6BAZ 6BB0 6BB1 6BB2 6BB3 6MV8 6MVA 6Q0D 6Q13 6SBU 6SBV 6ZZR 7M2N 8FW6 9BK2 9BK3
Enriched GO Terms of Interacting Partners?		Telomeric DNA Binding Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Via Telomerase Shelterin Complex Nuclear Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Telomere Capping Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Chromosome Organization Telomere Maintenance Positive Regulation Of Chromosome Organization Negative Regulation Of Biosynthetic Process Regulation Of Chromosome Organization Telomere Organization Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Chromosome, Telomeric Region Response To Metal Ion Telomere Maintenance Via Telomerase Negative Regulation Of Metabolic Process Protein-containing Complex Binding RNA-templated DNA Biosynthetic Process DNA Biosynthetic Process Nucleic Acid Metabolic Process Telomere Maintenance Via Telomere Lengthening Macromolecule Metabolic Process Liver Development Inward Rectifying Potassium Channel Nucleobase-containing Compound Metabolic Process Regulation Of DNA Replication Regeneration ATP-activated Inward Rectifier Potassium Channel Activity Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of DNA Biosynthetic Process Response To Xenobiotic Stimulus Positive Regulation Of Organelle Organization Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere
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