ACD and DCX

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		ACD	DCX
Gene Name		adrenocortical dysplasia homolog (mouse)	doublecortin
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm	Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Neuron Projection
	Molecular Function	DNA Binding Protein Binding DNA Polymerase Binding	Protein Binding Microtubule Binding Protein Kinase Binding
	Biological Process	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Segmentation Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region	Neuron Migration Nervous System Development Axon Guidance Central Nervous System Development Brain Development Central Nervous System Projection Neuron Axonogenesis Intracellular Signal Transduction Axon Extension Dendrite Morphogenesis
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis	Axon guidance Neurofascin interactions L1CAM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		59 interactors: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	29 interactors: ACD AP1M1 AP2M1 APP CALCOCO2 CDK5 FBXO25 GOLGA2 IKZF1 KIFC3 KRT40 KRTAP10-8 MEOX1 MID2 NFASC PAFAH1B1 POT1 PPP1CA PPP1R9B RINT1 SPAG5 SPP1 TERF1 TINF2 TRIM23 TRIM27 TRIM39 USP9X ZBTB5
Entrez ID		65057	1641
HPRD ID		12417	02127
Ensembl ID		ENSG00000102977	ENSG00000077279
Uniprot IDs		Q96AP0	A8K340 B4DM53 O43602
PDB IDs		2I46	1MJD 2BQQ 2XRP 4ATU
Enriched GO Terms of Interacting Partners?		Organelle Organization Protein Folding Carbohydrate Catabolic Process Substantia Nigra Development Neural Nucleus Development 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Nervous System Development Catabolic Process Cellular Component Assembly Midbrain Development Glycolytic Process Multicellular Organismal Development Negative Regulation Of Telomere Maintenance Via Telomerase Generation Of Neurons Telomere Assembly Pyruvate Metabolic Process Neurogenesis Developmental Process Negative Regulation Of Telomere Maintenance Monosaccharide Metabolic Process Regulation Of Cellular Protein Metabolic Process Brain Development Cellular Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Head Development Glucose Metabolic Process Neuron Projection Development Neuron Projection Morphogenesis Telomere Maintenance Cell Differentiation Neuron Differentiation Regulation Of Protein Metabolic Process System Development DNA Duplex Unwinding DNA Geometric Change Regulation Of Telomere Maintenance Cellular Process Neuron Development Adherens Junction Organization Central Nervous System Development Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Negative Regulation Of DNA Metabolic Process Protein Polymerization Regulation Of Signaling Innate Immune Response DNA Metabolic Process	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Replication Regulation Of Telomerase Activity Negative Regulation Of Cellular Metabolic Process Telomere Maintenance Cell Cycle Negative Regulation Of Chromosome Organization Regulation Of Cellular Component Organization Negative Regulation Of DNA Metabolic Process Regulation Of Organelle Organization Cell Division Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Biosynthetic Process Organelle Organization Regulation Of DNA Replication Regulation Of Developmental Growth Protein Localization To Chromosome, Telomeric Region Telomere Capping Regulation Of DNA Biosynthetic Process Movement Of Cell Or Subcellular Component Axonogenesis Cellular Component Assembly Protein Localization Positive Regulation Of Telomerase Activity Neuron Projection Development Cellular Localization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Locomotion Regulation Of Growth Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Negative Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Neuron Development Immune System Process Positive Regulation Of Telomere Maintenance Hippocampus Development Positive Regulation Of Organelle Organization Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Cell Morphogenesis Involved In Differentiation Forebrain Development Developmental Cell Growth Negative Regulation Of Viral Release From Host Cell Neuron Differentiation
Tagcloud ?		acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86	17p13 classical deletions disrupt epilepsy frontal gradient lis lis1 lissencephaly malformation mutations occipital overlapping parietal proline q23 repeats retardation sequencing sexes southern splice sporadic though truncation wd40 xlis xq22
Tagcloud (Difference) ?		acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86	17p13 classical deletions disrupt epilepsy frontal gradient lis lis1 lissencephaly malformation mutations occipital overlapping parietal proline q23 repeats retardation sequencing sexes southern splice sporadic though truncation wd40 xlis xq22
Tagcloud (Intersection) ?