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ACD and APOBEC3F
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
ACD
APOBEC3F
Description
ACD shelterin complex subunit and telomerase recruitment factor
apolipoprotein B mRNA editing enzyme catalytic subunit 3F
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Telomerase Holoenzyme Complex
Nuclear Body
Shelterin Complex
P-body
Nucleus
Cytoplasm
Apolipoprotein B MRNA Editing Enzyme Complex
Ribonucleoprotein Complex
Molecular Function
DNA Binding
Protein Binding
Telomerase Inhibitor Activity
Telomeric DNA Binding
Protein-containing Complex Binding
DNA Polymerase Binding
RNA Binding
Catalytic Activity
Cytidine Deaminase Activity
Protein Binding
Zinc Ion Binding
Hydrolase Activity
Identical Protein Binding
Metal Ion Binding
Biological Process
Telomere Maintenance
Skeletal System Development
Urogenital System Development
Intracellular Protein Transport
Telomere Maintenance Via Telomerase
Telomere Capping
Embryonic Limb Morphogenesis
Protection From Non-homologous End Joining At Telomere
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Segmentation
Protein Localization To Chromosome, Telomeric Region
Establishment Of Protein Localization To Telomere
Regulation Of Establishment Of Protein Localization To Telomere
Positive Regulation Of Defense Response To Virus By Host
Immune System Process
Transposable Element Silencing
Negative Regulation Of Macromolecule Biosynthetic Process
Base Conversion Or Substitution Editing
Cytidine To Uridine Editing
Positive Regulation Of Gene Expression Via Chromosomal CpG Island Demethylation
Clearance Of Foreign Intracellular DNA
Negative Regulation Of Viral Genome Replication
Innate Immune Response
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Negative Regulation Of Viral Process
Defense Response To Virus
DNA Cytosine Deamination
Antiviral Innate Immune Response
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Hemoglobin levels (
32327693
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
64 interacting genes:
ACTB
ADPRH
AFAP1L2
AIPL1
ANKMY2
ANXA8L1
APOBEC3F
BAG3
CKB
CTTN
DBN1
DBNL
DCX
DPYSL3
EIF3G
EIF4B
ENO2
ENSA
FAM131B
FBXW7
FKBP6
GAPDH
HSP90AB1
IPO5
IVL
LASP1
LDHA
LGALSL
LLGL1
LRRC25
NCDN
NTAQ1
NUDC
NUDCD2
PAGE2
PDLIM2
PEX5
PFKP
PGM2
POT1
RBKS
RECQL4
RGS3
RPSA
SBDS
STIP1
STUB1
SULT1C2
TAGLN
TBC1D10A
TBCD
TINF2
TOMM34
TRIM15
TRIM16
TRIM55
TRIM63
TUBB2A
TUBB4B
USP7
XRCC6
YWHAE
ZFP36L1
ZNF790
5 interacting genes:
ACD
APOBEC3G
ARIH2
RNF7
TINF2
Entrez ID
65057
200316
HPRD ID
12417
16415
Ensembl ID
ENSG00000102977
ENSG00000128394
Uniprot IDs
A0A8Q3WM11
Q96AP0
Q8IUX4
PDB IDs
2I46
5H65
5I2X
5I2Y
5UN7
5XYF
7QXA
7QXB
7QXS
7S1T
7TRE
8SOJ
8SOK
3WUS
4IOU
4J4J
5HX4
5HX5
5W2M
5ZVA
5ZVB
6NIL
Enriched GO Terms of Interacting Partners
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Cytoplasm
Cytosol
Cadherin Binding
Carbohydrate Catabolic Process
Nuclear Telomere Cap Complex
Protein Folding Chaperone Complex
Substantia Nigra Development
ADP Catabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Glycolytic Process
Telomere Maintenance
Cellular Response To Heat
ADP Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Nucleoside Diphosphate Catabolic Process
Monosaccharide Metabolic Process
Ribonucleoside Diphosphate Catabolic Process
Unfolded Protein Binding
Telomeric D-loop Binding
Telomere Assembly
Organelle Organization
Neural Nucleus Development
Pyruvate Metabolic Process
Glucose Metabolic Process
Telomere Organization
Protein Folding
Cortical Cytoskeleton
Glucose Catabolic Process
Telomeric DNA Binding
Protein Binding
Shelterin Complex
Ribonucleoside Diphosphate Metabolic Process
Purine Ribonucleotide Catabolic Process
Structural Constituent Of Postsynaptic Actin Cytoskeleton
Cytoskeleton Organization
Cytoskeleton
Microtubule Cytoskeleton Organization
Nucleoside Diphosphate Metabolic Process
Protein Stabilization
Chaperone-mediated Autophagy
Microtubule
Response To Heat
Purine Nucleotide Catabolic Process
Nitric-oxide Synthase Regulator Activity
TPR Domain Binding
Hexose Metabolic Process
Microtubule Cytoskeleton
Intercellular Bridge
Telomeric D-loop Disassembly
Hsp90 Protein Binding
Telomere Assembly
Shelterin Complex
Response To Virus
Nuclear Telomere Cap Complex
Protein Localization To Chromosome, Telomeric Region
Telomere Capping
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Cul5-RING Ubiquitin Ligase Complex
Negative Regulation Of Telomere Maintenance Via Telomerase
Growth Hormone Receptor Signaling Pathway
Telomeric DNA Binding
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Telomere Maintenance
Defense Response To Virus
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Response To Other Organism
Positive Regulation Of Telomere Maintenance
Immune Response
Negative Regulation Of Chromosome Organization
DCTP Deaminase Activity
Regulation Of DNA Biosynthetic Process
Response To External Biotic Stimulus
Macromolecule Metabolic Process
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Protein Localization To Chromosome
Regulation Of Telomere Maintenance
Perinucleolar Chromocenter
Telomere Organization
Negative Regulation Of DNA Metabolic Process
Innate Immune Response
Interleukin-12 Receptor Complex
Negative Regulation Of Focal Adhesion Disassembly
Negative Regulation Of Cellular Component Organization
Interleukin-23 Receptor Complex
NEDD8 Ligase Activity
DNA Metabolic Process
Defense Response To Symbiont
Chromosome, Telomeric Region
Defense Response To Other Organism
Immune System Process
NEDD8 Transferase Activity
Interleukin-23-mediated Signaling Pathway
Positive Regulation Of NK T Cell Proliferation
Phosphocreatine Biosynthetic Process
Apolipoprotein B MRNA Editing Enzyme Complex
Regulation Of Establishment Of Protein Localization To Telomere
Regulation Of Establishment Of Protein Localization To Chromosome
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Tagcloud (Difference)
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Tagcloud (Intersection)
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