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LDHA and DYNLL1
Number of citations of the paper that reports this interaction (PubMedID
14760703
)
0
Data Source:
HPRD
(in vitro)
LDHA
DYNLL1
Description
lactate dehydrogenase A
dynein light chain LC8-type 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Membrane
Sperm Fibrous Sheath
Extracellular Exosome
Oxidoreductase Complex
Kinetochore
Nucleus
Chromosome
Cytoplasm
Mitochondrion
Centrosome
Cytosol
Cytoskeleton
Cytoplasmic Dynein Complex
Microtubule
Microtubule Associated Complex
Plasma Membrane
Cilium
COP9 Signalosome
Microtubule Cytoskeleton
Membrane
Secretory Granule
Dynein Complex
Site Of Double-strand Break
Tertiary Granule Membrane
Mitotic Spindle
Ciliary Tip
Ficolin-1-rich Granule Membrane
Axon Cytoplasm
Molecular Function
Catalytic Activity
Lactate Dehydrogenase Activity
L-lactate Dehydrogenase (NAD+) Activity
Protein Binding
Oxidoreductase Activity
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Identical Protein Binding
Cadherin Binding
Enzyme Inhibitor Activity
Protein Binding
Enzyme Binding
Nitric-oxide Synthase Regulator Activity
Nitric-oxide Synthase Inhibitor Activity
Identical Protein Binding
Protein-containing Complex Binding
Dynein Intermediate Chain Binding
Deoxyribonuclease Inhibitor Activity
Scaffold Protein Binding
Biological Process
Lactate Metabolic Process
Glycolytic Process
Glucose Catabolic Process To Lactate Via Pyruvate
Carboxylic Acid Metabolic Process
Substantia Nigra Development
Pyruvate Catabolic Process
Apoptotic Process
DNA Damage Response
Microtubule-based Process
Spermatid Development
Substantia Nigra Development
Positive Regulation Of Intracellular Transport
Intraciliary Retrograde Transport
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Negative Regulation Of Phosphorylation
Motile Cilium Assembly
Negative Regulation Of Nitric Oxide Biosynthetic Process
DNA Strand Resection Involved In Replication Fork Processing
Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing
Pathways
Pyruvate metabolism
Regulation of pyruvate metabolism
Activation of BIM and translocation to mitochondria
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Macroautophagy
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
RHO GTPases Activate Formins
Neutrophil degranulation
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
AURKA Activation by TPX2
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Drugs
NADH
Etheno-NAD
Nicotinamide
Oxamic Acid
Stiripentol
Copper
Artenimol
Diseases
GWAS
Amyloid A serum levels (
21124955
)
Serum metabolite levels (
33031748
)
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Immature fraction of reticulocytes (
27863252
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Reading disability or specific language impairment (pleiotropy) (
25065397
)
Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) (
25065397
)
Reticulocyte count (
27863252
32888494
)
Reticulocyte fraction of red cells (
27863252
32888494
)
Interacting Genes
21 interacting genes:
ABCC9
ACD
CEBPA
DUX4
DYNLL1
FGFR1
GSK3A
HNRNPD
HULC
KCNJ11
MAPK10
NDRG1
PCNA
POT1
PTPRF
SRPK2
TERF1
TINF2
UPF2
XRN1
YWHAQ
108 interacting genes:
ACTB
ACTC1
ACTG1
ALDOA
AMOTL2
B3GALT4
BACH1
BCAS1
BCL2L11
BMF
C14orf119
C19orf44
CA2
CACNB1
CCDC28A
CIMAP1A
CLIP2
COXFA4L2
CS
DAZ1
DCTN5
DLG4
DLGAP1
DNAJB9
DNM2
DNM3
DNMT1
DPPA3
DYNC1H1
DYNC1I1
DYRK1A
EEF1A1
ERG28
FAM153A
FAM53B
GABARAPL1
GABARAPL2
GAPDH
GLUD1
GLUL
GNL3L
GPHN
GPRIN2
GRIN3A
HIP1R
HMBOX1
HOMER3
HSPA8
IHO1
INPP1
IQUB
KANK2
LDHA
MAP1B
MARK3
MAST2
ME2
MORC3
MORN3
MRE11
MTA1
MTR
MYO10
MYO5A
NDEL1
NFKBIA
NOS1
NRF1
NTRK1
NTRK2
NTRK3
OR7C2
OTUD6A
PAK1
PAN2
PARD3
PAX6
PCM1
PFKM
PFKP
PKIA
PKIB
PKIG
POLH
PPP3R2
RAB4A
RACK1
RASGRP4
REDIC1
RGS2
SHROOM3
SLC13A1
SMCP
TERT
THAP10
THAP8
TNFRSF14
TP53BP1
TRIM54
TSNARE1
TUBA3C
TUBB
TXNDC17
VIM
ZHX1
ZMYND11
ZNF354A
ZNF710
Entrez ID
3939
8655
HPRD ID
01025
03334
Ensembl ID
ENSG00000134333
ENSG00000088986
Uniprot IDs
P00338
V9HWB9
P63167
Q6FGH9
PDB IDs
1I10
4AJP
4JNK
4L4R
4L4S
4M49
4OJN
4OKN
4QO7
4QO8
4QSM
4QT0
4R68
4R69
4RLS
4ZVV
5IXS
5IXY
5W8H
5W8I
5W8J
5W8K
5W8L
5ZJD
5ZJE
5ZJF
6BAD
6BAG
6BAX
6BAZ
6BB0
6BB1
6BB2
6BB3
6MV8
6MVA
6Q0D
6Q13
6SBU
6SBV
6ZZR
7M2N
8FW6
9BK2
9BK3
1CMI
3ZKE
3ZKF
6GZJ
6GZL
6RLB
6SC2
7D35
8PR0
8PR1
8PTK
8RGG
Enriched GO Terms of Interacting Partners
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Telomeric DNA Binding
Regulation Of DNA Biosynthetic Process
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Telomere Maintenance Via Telomerase
Shelterin Complex
Nuclear Telomere Cap Complex
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance
Telomere Capping
Regulation Of DNA Metabolic Process
Regulation Of Telomere Maintenance
Telomere Assembly
Negative Regulation Of DNA Metabolic Process
Positive Regulation Of Telomere Maintenance
Positive Regulation Of DNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Chromosome Organization
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Negative Regulation Of Biosynthetic Process
Regulation Of Chromosome Organization
Telomere Organization
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Chromosome, Telomeric Region
Response To Metal Ion
Telomere Maintenance Via Telomerase
Negative Regulation Of Metabolic Process
Protein-containing Complex Binding
RNA-templated DNA Biosynthetic Process
DNA Biosynthetic Process
Nucleic Acid Metabolic Process
Telomere Maintenance Via Telomere Lengthening
Macromolecule Metabolic Process
Liver Development
Inward Rectifying Potassium Channel
Nucleobase-containing Compound Metabolic Process
Regulation Of DNA Replication
Regeneration
ATP-activated Inward Rectifier Potassium Channel Activity
Regulation Of Establishment Of Protein Localization To Telomere
Positive Regulation Of DNA Biosynthetic Process
Response To Xenobiotic Stimulus
Positive Regulation Of Organelle Organization
Regulation Of Establishment Of Protein Localization To Chromosome
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Cytoskeleton
Microtubule
Cytoplasm
Postsynaptic Density
Microtubule Binding
Neurotrophin Receptor Activity
Neurotrophin Binding
Cytosol
Pyruvate Metabolic Process
Neuron Projection Morphogenesis
Nucleotide Binding
Cell Projection Morphogenesis
Glycolytic Process
Fructose 1,6-bisphosphate Metabolic Process
Cytoskeleton Organization
Actin Filament
Identical Protein Binding
ADP Catabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Microtubule-based Process
Apical Junction Complex
ADP Metabolic Process
Nucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Positive Regulation Of Cellular Component Biogenesis
Replication Fork
CAMP-dependent Protein Kinase Inhibitor Activity
Cytoskeleton-dependent Intracellular Transport
Dendritic Spine
Organelle Organization
Axon
Establishment Of Organelle Localization
Axonogenesis
Microtubule Associated Complex
Carbohydrate Catabolic Process
Peptidyl-cysteine S-nitrosylase Activity
6-phosphofructokinase Activity
6-phosphofructokinase Complex
Beta-tubulin Binding
Ribonucleoside Diphosphate Metabolic Process
Purine Ribonucleotide Catabolic Process
Microtubule Cytoskeleton Organization
Substantia Nigra Development
Negative Regulation Of Protein Import Into Nucleus
Myelination In Peripheral Nervous System
Regulation Of Transport
Nucleoside Diphosphate Metabolic Process
Regulation Of Transepithelial Transport
Calyx Of Held
Fructose-6-phosphate Binding
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Tagcloud (Difference)
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Tagcloud (Intersection)
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