ACD and DPYSL3

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		ACD	DPYSL3
Gene Name		adrenocortical dysplasia homolog (mouse)	dihydropyrimidinase-like 3
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm	Extracellular Space Cytosol Lamellipodium Growth Cone Filamentous Actin Cell Body Exocytic Vesicle
	Molecular Function	DNA Binding Protein Binding DNA Polymerase Binding	Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides SH3 Domain Binding Chondroitin Sulfate Binding Phosphoprotein Binding
	Biological Process	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Segmentation Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region	Pyrimidine Nucleobase Catabolic Process Axon Guidance Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Migration Response To Axon Injury Actin Filament Bundle Assembly Protein Homooligomerization Positive Regulation Of Filopodium Assembly Actin Crosslink Formation Cellular Response To Cytokine Stimulus
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis	Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		59 interactors: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	8 interactors: ACD CRMP1 DISC1 DPYSL2 DPYSL5 POT1 TERF1 TNIK
Entrez ID		65057	1809
HPRD ID		12417	03104
Ensembl ID		ENSG00000102977	ENSG00000113657
Uniprot IDs		Q96AP0	Q14195 Q6DEN2 Q8IXW6
PDB IDs		2I46	4BKN
Enriched GO Terms of Interacting Partners?		Organelle Organization Protein Folding Carbohydrate Catabolic Process Substantia Nigra Development Neural Nucleus Development 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Nervous System Development Catabolic Process Cellular Component Assembly Midbrain Development Glycolytic Process Multicellular Organismal Development Negative Regulation Of Telomere Maintenance Via Telomerase Generation Of Neurons Telomere Assembly Pyruvate Metabolic Process Neurogenesis Developmental Process Negative Regulation Of Telomere Maintenance Monosaccharide Metabolic Process Regulation Of Cellular Protein Metabolic Process Brain Development Cellular Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Head Development Glucose Metabolic Process Neuron Projection Development Neuron Projection Morphogenesis Telomere Maintenance Cell Differentiation Neuron Differentiation Regulation Of Protein Metabolic Process System Development DNA Duplex Unwinding DNA Geometric Change Regulation Of Telomere Maintenance Cellular Process Neuron Development Adherens Junction Organization Central Nervous System Development Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Negative Regulation Of DNA Metabolic Process Protein Polymerization Regulation Of Signaling Innate Immune Response DNA Metabolic Process	Negative Regulation Of Telomere Maintenance Via Telomerase Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Pyrimidine Nucleobase Metabolic Process Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Telomere Assembly Telomere Capping Telomere Maintenance Positive Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Regulation Of Cellular Component Organization Regulation Of DNA Replication Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Chromosome Organization Telomere Maintenance Via Telomere Lengthening Generation Of Neurons Neurogenesis Organelle Organization Regulation Of Neuron Projection Development Positive Regulation Of DNA Replication Axon Guidance Developmental Process Cell Projection Organization Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Nervous System Development Regulation Of Cell Projection Organization Locomotion Axonogenesis System Development Regulation Of Neuron Differentiation Homeostatic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Transferase Activity Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Movement Of Cell Or Subcellular Component Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Formation Via Telomerase
Tagcloud ?		acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86
Tagcloud (Difference) ?		acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86
Tagcloud (Intersection) ?