LSM1 and VPS11

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		LSM1	VPS11
Gene Name		LSM1, U6 small nuclear RNA associated	vacuolar protein sorting 11 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Cytoplasm Cytosol	Lysosome Lysosomal Membrane Endosome Late Endosome Endocytic Vesicle HOPS Complex Late Endosome Membrane
	Molecular Function	RNA Cap Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding Protein Binding Zinc Ion Binding Syntaxin Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Histone MRNA Catabolic Process	Intracellular Protein Transport Vesicle-mediated Transport
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Schizophrenia ( 22037555)
Protein-Protein Interactions		25 interactors: CLIC1 EXOSC6 EXOSC8 GLUD1 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TMEM214 UPF2 UXT VPS11	25 interactors: BCAR1 BMI1 GGA3 KDM1A KIAA0368 KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MARK3 MON1B RNF181 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2U UVRAG VPS16 VPS18 VPS33A VPS45
Entrez ID		27257	55823
HPRD ID		06281	12258
Ensembl ID		ENSG00000175324	ENSG00000160695
Uniprot IDs		O15116	Q9H270
PDB IDs
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process MRNA Metabolic Process Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process RNA Splicing Catabolic Process MRNA Processing Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Processing Gene Expression RNA Metabolic Process NcRNA Metabolic Process RRNA Processing RRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Ribosome Biogenesis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Immunoglobulin Production Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration Mitotic Cell Cycle Phase Transition Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity	Vesicle Organization Vesicle Fusion Vesicle-mediated Transport Organelle Fusion Vesicle Docking Protein Transport Membrane Docking Establishment Of Protein Localization Membrane Fusion Vesicle Docking Involved In Exocytosis Protein Localization Viral Life Cycle Regulation Of Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Cellular Component Organization Intracellular Transport Establishment Of Localization In Cell Viral Entry Into Host Cell Organelle Organization Entry Into Host Cell Membrane Organization Regulation Of SNARE Complex Assembly Cellular Protein Localization Viral Budding Cellular Localization Endosomal Transport Interaction With Host Viral Process Transport Protein Ubiquitination Virion Assembly Protein Modification By Small Protein Conjugation Protein Catabolic Process Exocytosis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Endosome Organization Histone Ubiquitination Protein Polyubiquitination Regulation Of Vesicle Fusion Regulation Of Protein Localization Protein Autoubiquitination Regulation Of Vacuole Fusion, Non-autophagic Ubiquitin-dependent Endocytosis Positive Regulation Of Receptor Localization To Synapse Regulation Of Primitive Erythrocyte Differentiation Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		activators cerevisiae codons dcp1 dcp2 deadenylation decapping decay defines dhh1 edc1 edc2 edc3 hybrid nmd nonsense overlapping pat1 premature proper recruit saccharomyces stimulators termed termination transcripts upf1 upf2 upf3
Tagcloud (Difference) ?		activators cerevisiae codons dcp1 dcp2 deadenylation decapping decay defines dhh1 edc1 edc2 edc3 hybrid nmd nonsense overlapping pat1 premature proper recruit saccharomyces stimulators termed termination transcripts upf1 upf2 upf3
Tagcloud (Intersection) ?