VPS11 and VPS18

Number of citations of the paper that reports this interaction (PMID 11382755)
23

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		VPS11	VPS18
Gene Name		vacuolar protein sorting 11 homolog (S. cerevisiae)	vacuolar protein sorting 18 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Late Endosome Endocytic Vesicle HOPS Complex Late Endosome Membrane	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Actin Filament HOPS Complex Late Endosome Membrane
	Molecular Function	Nucleotide Binding Protein Binding Zinc Ion Binding Syntaxin Binding	Actin Binding Protein Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome Organization Lysosome Organization Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell
Pathways
Drugs
Diseases
GWAS			Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		25 interactors: BCAR1 BMI1 GGA3 KDM1A KIAA0368 KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MARK3 MON1B RNF181 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2U UVRAG VPS16 VPS18 VPS33A VPS45	18 interactors: AKTIP COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45
Entrez ID		55823	57617
HPRD ID		12258	09776
Ensembl ID		ENSG00000160695	ENSG00000104142
Uniprot IDs		Q9H270	Q9P253
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Organization Vesicle Fusion Vesicle-mediated Transport Organelle Fusion Vesicle Docking Protein Transport Membrane Docking Establishment Of Protein Localization Membrane Fusion Vesicle Docking Involved In Exocytosis Protein Localization Viral Life Cycle Regulation Of Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Cellular Component Organization Intracellular Transport Establishment Of Localization In Cell Viral Entry Into Host Cell Organelle Organization Entry Into Host Cell Membrane Organization Regulation Of SNARE Complex Assembly Cellular Protein Localization Viral Budding Cellular Localization Endosomal Transport Interaction With Host Viral Process Transport Protein Ubiquitination Virion Assembly Protein Modification By Small Protein Conjugation Protein Catabolic Process Exocytosis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Endosome Organization Histone Ubiquitination Protein Polyubiquitination Regulation Of Vesicle Fusion Regulation Of Protein Localization Protein Autoubiquitination Regulation Of Vacuole Fusion, Non-autophagic Ubiquitin-dependent Endocytosis Positive Regulation Of Receptor Localization To Synapse Regulation Of Primitive Erythrocyte Differentiation Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process	Vesicle-mediated Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Establishment Of Localization In Cell Intracellular Protein Transport Cellular Localization Vesicle Fusion Cellular Protein Localization Transport Organelle Fusion Vesicle Organization Membrane Fusion Vesicle Docking Endosomal Transport Early Endosome To Late Endosome Transport Membrane Docking Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Vesicle Docking Involved In Exocytosis Membrane Organization Vacuolar Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Organelle Organization Organelle Localization Viral Entry Into Host Cell Entry Into Host Cell Vesicle Localization Viral Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Protein Localization To Plasma Membrane Histone H2B Acetylation Regulation Of Vacuole Fusion, Non-autophagic Positive Regulation Of Receptor Localization To Synapse Regulation Of DNA-templated Transcription In Response To Stress Lysosome Organization Positive Regulation Of Protein Binding Exocytosis N-terminal Peptidyl-lysine Acetylation Regulation Of Protein Localization Cellular Response To Hypoxia Regulation Of Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Interaction With Host Vacuole Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Response To Oxygen Levels Regulation Of Tubulin Deacetylation
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