LSM1 and NARS

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		LSM1	NARS
Gene Name		LSM1, U6 small nuclear RNA associated	asparaginyl-tRNA synthetase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Cytoplasm Cytosol	Cytoplasm Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	RNA Cap Binding Protein Binding Poly(A) RNA Binding	Nucleic Acid Binding Asparagine-tRNA Ligase Activity ATP Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Histone MRNA Catabolic Process	TRNA Aminoacylation For Protein Translation Asparaginyl-tRNA Aminoacylation Gene Expression
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay	Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs			L-Asparagine
Diseases
GWAS		Schizophrenia ( 22037555)
Protein-Protein Interactions		25 interactors: CLIC1 EXOSC6 EXOSC8 GLUD1 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TMEM214 UPF2 UXT VPS11	2 interactors: ATXN1 LSM1
Entrez ID		27257	4677
HPRD ID		06281	00154
Ensembl ID		ENSG00000175324	ENSG00000134440
Uniprot IDs		O15116	O43776
PDB IDs
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process MRNA Metabolic Process Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process RNA Splicing Catabolic Process MRNA Processing Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Processing Gene Expression RNA Metabolic Process NcRNA Metabolic Process RRNA Processing RRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Ribosome Biogenesis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Immunoglobulin Production Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration Mitotic Cell Cycle Phase Transition Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity	RNA Processing Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Histone MRNA Catabolic Process Histone MRNA Metabolic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Tagcloud ?		activators cerevisiae codons dcp1 dcp2 deadenylation decapping decay defines dhh1 edc1 edc2 edc3 hybrid nmd nonsense overlapping pat1 premature proper recruit saccharomyces stimulators termed termination transcripts upf1 upf2 upf3	affymetrix aimps aminoacyl arsn arss atlas atp5c1 cars druggable dtgs fars gbm hsp90aa1 integrative interactors krt10 med12 multiforme pard3 pathologically ppis qars rxrb synthetases tcga thra vars versatility
Tagcloud (Difference) ?		activators cerevisiae codons dcp1 dcp2 deadenylation decapping decay defines dhh1 edc1 edc2 edc3 hybrid nmd nonsense overlapping pat1 premature proper recruit saccharomyces stimulators termed termination transcripts upf1 upf2 upf3	affymetrix aimps aminoacyl arsn arss atlas atp5c1 cars druggable dtgs fars gbm hsp90aa1 integrative interactors krt10 med12 multiforme pard3 pathologically ppis qars rxrb synthetases tcga thra vars versatility
Tagcloud (Intersection) ?