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LSM1 and GRHPR
Number of citations of the paper that reports this interaction (PMID
15231747
)
44
Data Source:
HPRD
(two hybrid)
LSM1
GRHPR
Gene Name
LSM1, U6 small nuclear RNA associated
glyoxylate reductase/hydroxypyruvate reductase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasmic MRNA Processing Body
Nucleus
Cytoplasm
Cytosol
Cytoplasm
Peroxisomal Matrix
Cytosol
Extracellular Vesicular Exosome
Molecular Function
RNA Cap Binding
Protein Binding
Poly(A) RNA Binding
Glycerate Dehydrogenase Activity
Hydroxypyruvate Reductase Activity
Glyoxylate Reductase (NADP) Activity
Carboxylic Acid Binding
Protein Homodimerization Activity
NAD Binding
NADPH Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
RNA Splicing, Via Transesterification Reactions
MRNA Processing
RNA Splicing
Gene Expression
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Histone MRNA Catabolic Process
Excretion
Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Dicarboxylic Acid Metabolic Process
Small Molecule Metabolic Process
Glyoxylate Metabolic Process
Protein Oligomerization
Oxidation-reduction Process
Pathways
mRNA decay by 5' to 3' exoribonuclease
Deadenylation-dependent mRNA decay
Glyoxylate metabolism
Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Schizophrenia (
22037555
)
Protein-Protein Interactions
25 interactors:
CLIC1
EXOSC6
EXOSC8
GLUD1
GRHPR
HSP90AA1
LSM2
LSM3
LSM4
LSM5
LSM6
LSM7
MPDU1
N4BP1
NARS
NDUFAF3
PSMB5
PSMB8
PTPRC
RRP1B
SMN1
TMEM214
UPF2
UXT
VPS11
6 interactors:
CDC7
FOS
GLS2
LIG4
LSM1
PTH2R
Entrez ID
27257
9380
HPRD ID
06281
05052
Ensembl ID
ENSG00000175324
ENSG00000137106
Uniprot IDs
O15116
Q9UBQ7
PDB IDs
2GCG
2H1S
2Q50
2WWR
Enriched GO Terms of Interacting Partners
?
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
RNA Catabolic Process
MRNA Metabolic Process
Cellular Macromolecule Catabolic Process
Aromatic Compound Catabolic Process
RNA Splicing
Catabolic Process
MRNA Processing
Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
RNA Processing
Gene Expression
RNA Metabolic Process
NcRNA Metabolic Process
RRNA Processing
RRNA Metabolic Process
Ribonucleoprotein Complex Biogenesis
Ribosome Biogenesis
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Cellular Metabolic Process
Cell Cycle Phase Transition
Negative Regulation Of Protein Ubiquitination
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Protein Ubiquitination
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Immunoglobulin Production
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Immunoglobulin Biosynthetic Process
Positive Regulation Of Hematopoietic Stem Cell Migration
Mitotic Cell Cycle Phase Transition
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Ligase Activity
DNA Ligation Involved In DNA Recombination
DNA-dependent DNA Replication
Cellular Response To Metal Ion
Double-strand Break Repair Via Break-induced Replication
Cellular Response To Inorganic Substance
Double-strand Break Repair
Positive Regulation Of Nuclear Cell Cycle DNA Replication
Lagging Strand Elongation
Pro-B Cell Differentiation
Conditioned Taste Aversion
DNA Recombination
DNA Metabolic Process
Establishment Of Integrated Proviral Latency
DNA Replication
Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Cellular Nitrogen Compound Metabolic Process
Immunoglobulin V(D)J Recombination
Establishment Of Viral Latency
Histone MRNA Catabolic Process
T Cell Receptor V(D)J Recombination
Regulation Of Nuclear Cell Cycle DNA Replication
DNA Ligation Involved In DNA Repair
Response To Metal Ion
Lymphoid Progenitor Cell Differentiation
Nitrogen Compound Metabolic Process
DNA Ligation
Sleep
Response To Gravity
Positive Regulation Of DNA-dependent DNA Replication
Nucleotide-excision Repair, DNA Gap Filling
Cellular Response To Lithium Ion
Cellular Response To Stress
Cell Division
Response To Radiation
Histone MRNA Metabolic Process
Response To Inorganic Substance
Single Strand Break Repair
Double-strand Break Repair Via Nonhomologous End Joining
Response To Immobilization Stress
Glutamate Secretion
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Positive Regulation Of Osteoclast Differentiation
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Isotype Switching
Tagcloud
?
activators
cerevisiae
codons
dcp1
dcp2
deadenylation
decapping
decay
defines
dhh1
edc1
edc2
edc3
hybrid
nmd
nonsense
overlapping
pat1
premature
proper
recruit
saccharomyces
stimulators
termed
termination
transcripts
upf1
upf2
upf3
Tagcloud (Difference)
?
activators
cerevisiae
codons
dcp1
dcp2
deadenylation
decapping
decay
defines
dhh1
edc1
edc2
edc3
hybrid
nmd
nonsense
overlapping
pat1
premature
proper
recruit
saccharomyces
stimulators
termed
termination
transcripts
upf1
upf2
upf3
Tagcloud (Intersection)
?