LSM1 and LSM3

Number of citations of the paper that reports this interaction (PMID 11920408)
2

Data Source:
HPRD (in vitro)

		LSM1	LSM3
Gene Name		LSM1, U6 small nuclear RNA associated	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Cytoplasm Cytosol	Nucleus Cytosol Catalytic Step 2 Spliceosome
	Molecular Function	RNA Cap Binding Protein Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Histone MRNA Catabolic Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome MRNA Processing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay	mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Schizophrenia ( 22037555)
Protein-Protein Interactions		25 interactors: CLIC1 EXOSC6 EXOSC8 GLUD1 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TMEM214 UPF2 UXT VPS11	28 interactors: CEP95 CLNS1A DLX4 EEF1A1 GDF9 GSTA1 KEAP1 LSM1 LSM10 LSM2 LSM5 LSM6 LSM7 LSM8 SF3B2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPG TCL1A THOC5 UTP14A WDR77 WDR83 XPC XRN2 YBX1
Entrez ID		27257	27258
HPRD ID		06281	06283
Ensembl ID		ENSG00000175324
Uniprot IDs		O15116	P62310
PDB IDs
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process MRNA Metabolic Process Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process RNA Splicing Catabolic Process MRNA Processing Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Processing Gene Expression RNA Metabolic Process NcRNA Metabolic Process RRNA Processing RRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Ribosome Biogenesis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Immunoglobulin Production Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration Mitotic Cell Cycle Phase Transition Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity	MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Ribonucleoprotein Complex Assembly NcRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA-templated Transcription, Termination RNA Catabolic Process Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Aromatic Compound Catabolic Process Nuclear-transcribed MRNA Catabolic Process Spliceosomal Complex Assembly MRNA Catabolic Process MRNA 3'-end Processing Cellular Macromolecule Catabolic Process Cellular Macromolecular Complex Assembly RNA 3'-end Processing Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Process Catabolic Process Maturation Of SSU-rRNA Transcription, DNA-templated RNA Biosynthetic Process Ribosomal Small Subunit Biogenesis Oocyte Growth Nucleotide-excision Repair, DNA Damage Recognition Cellular Component Assembly Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Progesterone Secretion Proteasomal Ubiquitin-independent Protein Catabolic Process CRD-mediated MRNA Stabilization
Tagcloud ?		activators cerevisiae codons dcp1 dcp2 deadenylation decapping decay defines dhh1 edc1 edc2 edc3 hybrid nmd nonsense overlapping pat1 premature proper recruit saccharomyces stimulators termed termination transcripts upf1 upf2 upf3
Tagcloud (Difference) ?		activators cerevisiae codons dcp1 dcp2 deadenylation decapping decay defines dhh1 edc1 edc2 edc3 hybrid nmd nonsense overlapping pat1 premature proper recruit saccharomyces stimulators termed termination transcripts upf1 upf2 upf3
Tagcloud (Intersection) ?