VPS11 and MARK3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		VPS11	MARK3
Gene Name		vacuolar protein sorting 11 homolog (S. cerevisiae)	MAP/microtubule affinity-regulating kinase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Late Endosome Endocytic Vesicle HOPS Complex Late Endosome Membrane	Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Protein Binding Zinc Ion Binding Syntaxin Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport	Protein Phosphorylation
Pathways
Drugs
Diseases
GWAS			Bone mineral density ( 22504420)
Protein-Protein Interactions		25 interactors: BCAR1 BMI1 GGA3 KDM1A KIAA0368 KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MARK3 MON1B RNF181 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2U UVRAG VPS16 VPS18 VPS33A VPS45	27 interactors: ANKRD7 ASB13 ATP6V0C CDC25C CHGB CPSF4 DYNLL1 FANCF HDAC7 KSR1 MAP2 MAPT MITF NOL11 PIM1 PKP2 PMPCB PNPLA2 PRKCQ SAAL1 SFN TCEA2 TTR VPS11 YWHAG YWHAQ YWHAZ
Entrez ID		55823	4140
HPRD ID		12258	04058
Ensembl ID		ENSG00000160695	ENSG00000075413
Uniprot IDs		Q9H270	P27448 Q86U11
PDB IDs			2QNJ 3FE3
Enriched GO Terms of Interacting Partners?		Vesicle Organization Vesicle Fusion Vesicle-mediated Transport Organelle Fusion Vesicle Docking Protein Transport Membrane Docking Establishment Of Protein Localization Membrane Fusion Vesicle Docking Involved In Exocytosis Protein Localization Viral Life Cycle Regulation Of Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Cellular Component Organization Intracellular Transport Establishment Of Localization In Cell Viral Entry Into Host Cell Organelle Organization Entry Into Host Cell Membrane Organization Regulation Of SNARE Complex Assembly Cellular Protein Localization Viral Budding Cellular Localization Endosomal Transport Interaction With Host Viral Process Transport Protein Ubiquitination Virion Assembly Protein Modification By Small Protein Conjugation Protein Catabolic Process Exocytosis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Endosome Organization Histone Ubiquitination Protein Polyubiquitination Regulation Of Vesicle Fusion Regulation Of Protein Localization Protein Autoubiquitination Regulation Of Vacuole Fusion, Non-autophagic Ubiquitin-dependent Endocytosis Positive Regulation Of Receptor Localization To Synapse Regulation Of Primitive Erythrocyte Differentiation Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Apoptotic Process Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Programmed Cell Death Cell Death Death Organelle Organization Apoptotic Signaling Pathway Regulation Of Organelle Organization Regulation Of Apoptotic Process Positive Regulation Of Transport Regulation Of Cellular Component Organization Regulation Of Cell Death Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Signal Transduction G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Apoptotic Process Multicellular Organismal Development Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death System Development Intracellular Signal Transduction Regulation Of Cellular Localization Regulation Of Establishment Of Protein Localization Substantia Nigra Development Protein Targeting Regulation Of Protein Localization Developmental Process Cellular Response To Insulin Stimulus Neural Nucleus Development Signaling Anatomical Structure Development Regulation Of Phosphorylation Protein Targeting To Mitochondrion Regulation Of Cellular Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Intracellular Protein Transport Cell Communication Negative Regulation Of Apoptotic Process Positive Regulation Of T-helper 2 Cell Activation
Tagcloud ?			acrylamide amiloride bbmv benzoyl border brush cariporide dihydro guanidine guanidino hnhe1 ic50 isopro isopropyl lap1 methane methylsulphonyl micromol nhe nhe1 nhe2 nhe3 ok opossum propenyl pylidene rbnhe2 s3226 sulphonate
Tagcloud (Difference) ?			acrylamide amiloride bbmv benzoyl border brush cariporide dihydro guanidine guanidino hnhe1 ic50 isopro isopropyl lap1 methane methylsulphonyl micromol nhe nhe1 nhe2 nhe3 ok opossum propenyl pylidene rbnhe2 s3226 sulphonate
Tagcloud (Intersection) ?