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VPS11 and UVRAG
Number of citations of the paper that reports this interaction (PubMedID
18552835
)
46
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
VPS11
UVRAG
Description
VPS11 core subunit of CORVET and HOPS complexes
UV radiation resistance associated
Image
No pdb structure
GO Annotations
Cellular Component
Lysosome
Lysosomal Membrane
Endosome
Early Endosome
Late Endosome
Autophagosome
Endosome Membrane
Membrane
Clathrin-coated Vesicle
Endocytic Vesicle
HOPS Complex
Cytoplasmic Vesicle
Late Endosome Membrane
CORVET Complex
Vesicle Tethering Complex
Lytic Vacuole
Autophagosome Membrane
Chromosome, Centromeric Region
Chromosome
Cytoplasm
Lysosome
Endosome
Early Endosome
Late Endosome
Autophagosome
Endoplasmic Reticulum
Centrosome
Midbody
Cytoplasmic Vesicle
Protein-containing Complex
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Phosphatidylinositol 3-kinase Complex, Class III
Phagocytic Vesicle
DNA-dependent Protein Kinase Complex
Molecular Function
Nucleotide Binding
Protein Binding
Zinc Ion Binding
Protein Domain Specific Binding
Syntaxin Binding
Protein-macromolecule Adaptor Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
SNARE Binding
Protein Binding
SH3 Domain Binding
Biological Process
Intracellular Protein Transport
Vesicle Docking Involved In Exocytosis
Autophagy
Endosome Organization
Vacuole Organization
Endosome To Lysosome Transport
Protein Transport
Vesicle-mediated Transport
Protein Ubiquitination
Regulation Of Protein Stability
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Endosomal Vesicle Fusion
Regulation Of SNARE Complex Assembly
Positive Regulation Of Protein Catabolic Process
Organelle Fusion
Regulation Of Organelle Assembly
Positive Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Early Endosome To Late Endosome Transport
DNA Repair
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Autophagy
DNA Damage Response
Spindle Organization
Chromosome Segregation
Centrosome Cycle
Regulation Of Autophagy
Vesicle-mediated Transport
Regulation Of Cytokinesis
Receptor Catabolic Process
SNARE Complex Assembly
Phosphatidylinositol-3-phosphate Biosynthetic Process
Protein-containing Complex Organization
Symbiont Entry Into Host Cell
Maintenance Of Golgi Location
Regulation Of Protein Serine/threonine Kinase Activity
Multivesicular Body Sorting Pathway
Autophagosome Maturation
Double-strand Break Repair Via Classical Nonhomologous End Joining
Positive Regulation Of Autophagosome Maturation
Pathways
SARS-CoV-2 modulates autophagy
Macroautophagy
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
SARS-CoV-2 modulates autophagy
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Body mass index (
29273807
)
Coronary artery disease (
29212778
33020668
)
HDL cholesterol levels (
32203549
)
Plateletcrit (
32888494
)
Asthma (
31619474
)
HDL cholesterol (
30275531
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Mean spheric corpuscular volume (
32888494
)
Stroke (
32693751
)
Thumb osteoarthritis severity (hand Klsum) (
33055079
)
Interacting Genes
33 interacting genes:
BCAR1
BMI1
ECPAS
EZR
GGA3
GRSF1
KDM1A
KRTAP10-3
KRTAP10-8
LRSAM1
LSM1
MARK3
MON1B
MSN
RAB7A
RDX
RILP
RNF181
STX1A
STX6
STX7
STX8
TFAP2B
TRIM32
TSG101
UBE2D2
UBE2L3
UBE2U
UVRAG
VPS16
VPS18
VPS33A
VPS45
10 interacting genes:
CSNK1A1
ITCH
MTOR
NEDD4
VPS11
VPS16
VPS18
VPS33B
YAP1
ZRANB1
Entrez ID
55823
7405
HPRD ID
12258
03929
Ensembl ID
ENSG00000160695
ENSG00000198382
Uniprot IDs
A0A087WXL6
B7Z879
Q9H270
Q9P2Y5
PDB IDs
7BL1
Enriched GO Terms of Interacting Partners
?
Late Endosome
Membrane Docking
Vesicle Organization
Organelle Membrane Fusion
Vesicle Fusion
Organelle Fusion
Endosome
Vesicle-mediated Transport
Intracellular Protein Transport
Membrane Fusion
Early Endosome
Vacuolar Transport
Endosome To Lysosome Transport
Intracellular Protein Localization
Lysosomal Transport
Positive Regulation Of Catabolic Process
Establishment Of Protein Localization
Protein Transport
Organelle Localization
Macromolecule Catabolic Process
Catabolic Process
Vesicle Docking
SNARE Binding
Regulation Of Protein Localization
Positive Regulation Of Protein Catabolic Process
Cellular Localization
Chloride Channel Inhibitor Activity
CORVET Complex
Clathrin-coated Vesicle
Intracellular Transport
Organelle Localization By Membrane Tethering
Positive Regulation Of Early Endosome To Late Endosome Transport
Autophagosome
Membrane Organization
Endosome Organization
Late Endosome Membrane
Positive Regulation Of Protein Localization To Early Endosome
SNAP Receptor Activity
Endosomal Transport
Positive Regulation Of Protein Localization To Endosome
Establishment Of Localization In Cell
Endosome Membrane
SNARE Complex
HOPS Complex
Autophagy
Autophagosome Maturation
Syntaxin Binding
Regulation Of SNARE Complex Assembly
Endosomal Vesicle Fusion
Positive Regulation Of Protein Metabolic Process
CORVET Complex
HOPS Complex
Vacuole Organization
Vesicle Tethering Complex
Lysosomal Transport
Vacuolar Transport
Endosome To Lysosome Transport
Regulation Of SNARE Complex Assembly
Endosomal Vesicle Fusion
Positive Regulation Of Protein Catabolic Process
Catabolic Process
Clathrin-coated Vesicle
Vesicle Fusion
Intracellular Protein Transport
Organelle Membrane Fusion
Endosome Membrane
Protein Modification Process
Early Endosome
Organelle Fusion
Regulation Of Protein Catabolic Process
Lysosomal Membrane
Late Endosome Membrane
Late Endosome
Membrane Fusion
Regulation Of Protein-containing Complex Assembly
Protein Metabolic Process
Post-translational Protein Modification
Cytoplasmic Vesicle
Negative Regulation Of Signal Transduction
Lysosome
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Positive Regulation Of Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Autophagosome
Endosome Organization
Regulation Of Cellular Component Organization
Protein Transport
Protein Ubiquitination
Autophagosome Assembly
Autophagy
Autophagosome Organization
Vesicle-mediated Transport
Vesicle Organization
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Proteolysis Involved In Protein Catabolic Process
Proteolysis
Intracellular Transport
Protein Modification By Small Protein Conjugation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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