RBM5 and DCX

Number of citations of the paper that reports this interaction (PubMedID 30217970)
38

Data Source:
BioGRID (two hybrid)

		RBM5	DCX
Description		RNA binding motif protein 5	doublecortin
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol	Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Cell Projection Neuron Projection
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Microtubule Binding Protein Kinase Binding
	Biological Process	Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing Apoptotic Process Negative Regulation Of Cell Population Proliferation RNA Splicing Positive Regulation Of Apoptotic Process	Neuron Migration Nervous System Development Central Nervous System Development Cell Differentiation Axoneme Assembly Intracellular Signal Transduction Retina Development In Camera-type Eye
Pathways		mRNA Splicing - Major Pathway	Neurofascin interactions
Drugs
Diseases			Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS		Age at first birth ( 27798627) Alanine aminotransferase levels ( 33547301) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Caffeine consumption from tea ( 33287642) Cortical surface area (MOSTest) ( 32665545) Dentures ( 31235808) Extremely high intelligence ( 29520040) HDL cholesterol ( 24097068) HDL cholesterol levels ( 30698716 28334899) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) Morning person ( 30696823) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		32 interacting genes: BCL2L1 CASK CIP2A CREBBP DCX DDX17 GAPDH ILF3 KIF19 KIF9 LIG4 LRIF1 LSM8 MED1 MEOX1 MEOX2 MIRLET7D MIRLET7E MIRLET7G MIRLET7I MLYCD NDEL1 PARD3B PCM1 PKP2 POMP RBM14 RNF10 SHANK3 WBP11 WDR77 ZDHHC17	39 interacting genes: ACD AP1M1 AP2M1 APP BICD2 CALCOCO2 CDK5 FBXO25 FSD2 GOLGA2 HOOK2 IKZF1 KIFC3 KRT40 KRTAP10-8 MAPK9 MEOX1 MEOX2 MID2 MTUS2 NFASC PAFAH1B1 POT1 PPP1CA PPP1R9B RBM5 RINT1 SPAG5 SPP1 TERF1 TINF2 TRIM23 TRIM27 TRIM39 USP9X VPS52 ZBTB10 ZBTB5 ZRANB1
Entrez ID		10181	1641
HPRD ID		06052	02127
Ensembl ID		ENSG00000003756	ENSG00000077279
Uniprot IDs		P52756	A0A1B0GWD1 A0A7P0T9C5 A0A804CF28 A8K340 O43602
PDB IDs		2LK0 2LK1 2LKZ 5MF9 5MFY 7PCV 7PDV	1MJD 2BQQ 2XRP 4ATU 5IKC 5IN7 5IO9 5IOI 5IP4 6FNZ 6REV 6RF2 6RF8 6RFD
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Somite Specification Regulatory NcRNA-mediated Gene Silencing Kinesin Complex RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Microtubule Binding Post-transcriptional Gene Silencing Transcription Coactivator Activity Microtubule Cytoskeleton Organization Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell MRNA Base-pairing Post-transcriptional Repressor Activity Positive Regulation Of RNA Metabolic Process Organelle Organization Cytoplasm Segment Specification Somite Development Nuclear Retinoic Acid Receptor Binding RNA Splicing MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Ribonucleoprotein Complex RNA Splicing, Via Transesterification Reactions Hematopoietic Stem Cell Differentiation Post-transcriptional Regulation Of Gene Expression MRNA Metabolic Process Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Keratinocyte Proliferation Negative Regulation Of Gene Expression Neuron Apoptotic Process Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing	Shelterin Complex Microtubule Binding Telomeric DNA Binding Nuclear Telomere Cap Complex Telomere Capping Telomere Assembly Intracellular Protein Localization Negative Regulation Of Telomere Maintenance Via Telomerase Intracellular Transport Establishment Of Localization In Cell Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Microtubule Negative Regulation Of Telomere Maintenance Cellular Localization Protein Transport Establishment Of Protein Localization Telomere Maintenance Chromosome, Telomeric Region Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cellular Component Organization Acetylcholine Receptor Activator Activity Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Cellular Component Organization Telomere Organization Cytoskeleton Growth Cone Organelle Organization Positive Regulation Of Organelle Organization Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance RNA-templated DNA Biosynthetic Process Negative Regulation Of Chromosome Organization Vesicle-mediated Transport Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Biosynthetic Process Regulation Of Organelle Organization Somite Specification Cell Division Regulation Of Establishment Of Protein Localization To Telomere Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Binding Positive Regulation Of Chromosome Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Supramolecular Fiber Organization Regulation Of Telomere Maintenance Chromosome Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?