RBM5 and LSM8

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		RBM5	LSM8
Gene Name		RNA binding motif protein 5	LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex	Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Nucleotide Binding DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Protein Binding U6 SnRNA Binding U6 SnRNA 3'-end Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Apoptotic Process Negative Regulation Of Cell Proliferation RNA Splicing Gene Expression Positive Regulation Of Apoptotic Process	MRNA Splicing, Via Spliceosome
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: BCL2L1 GAPDH ILF3 LIG4 LRIF1 LSM8 WBP11 WDR77 ZDHHC17	49 interactors: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FAM63A FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MGA MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPT10 SEPT5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		10181	51691
HPRD ID		06052	06288
Ensembl ID		ENSG00000003756
Uniprot IDs		P52756	A4D0W0 O95777
PDB IDs		2LK0 2LK1 2LKZ
Enriched GO Terms of Interacting Partners?		Neuron Apoptotic Process Neuron Death Response To Gamma Radiation RNA Splicing RNA Metabolic Process DNA Ligation Involved In DNA Recombination Peptidyl-cysteine S-trans-nitrosylation Apoptotic Process In Bone Marrow Negative Regulation Of Translation MRNA Processing MRNA Metabolic Process RNA Processing Response To Ionizing Radiation Suppression By Virus Of Host Apoptotic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Peptidyl-cysteine S-nitrosylation Negative Regulation Of Neuron Apoptotic Process Lagging Strand Elongation Pro-B Cell Differentiation Nucleobase-containing Compound Metabolic Process Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Negative Regulation Of Neuron Death Establishment Of Integrated Proviral Latency Positive Regulation Of Cell Proliferation Heterocycle Metabolic Process Negative Regulation Of Execution Phase Of Apoptosis Cellular Aromatic Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Neuron Apoptotic Process Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Response To Virus Cellular Nitrogen Compound Metabolic Process Regulation Of Translation Lymphoid Progenitor Cell Differentiation Apoptotic Process Gene Expression Cellular Response To Virus Regulation Of Neuron Death Modulation By Virus Of Host Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Programmed Cell Death Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane DNA Ligation Negative Regulation Of Anoikis Cell Death	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nucleobase-containing Compound Metabolic Process Aromatic Compound Catabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Processing RNA Processing Catabolic Process Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Metabolic Process Histone MRNA Metabolic Process Pentose Biosynthetic Process Metabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Spliceosomal Complex Assembly Dosage Compensation Ribonucleoprotein Complex Assembly Ribosome Biogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Glucose 6-phosphate Metabolic Process RRNA Processing NcRNA Metabolic Process Starch Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Response To Type III Interferon Dolichol Biosynthetic Process NADP Metabolic Process RRNA Metabolic Process Spliceosomal SnRNP Assembly Carbohydrate Biosynthetic Process D-gluconate Metabolic Process Response To Vitamin B2
Tagcloud ?		accompanied active apoptotic apparently bax caspase cord demonstrating employed establish expressions immunofluorescent labeling localization location modulating motif nervous neuronal pc12 probe promotes regulating sci spinal suppressor traumatic trigger unregulated
Tagcloud (Difference) ?		accompanied active apoptotic apparently bax caspase cord demonstrating employed establish expressions immunofluorescent labeling localization location modulating motif nervous neuronal pc12 probe promotes regulating sci spinal suppressor traumatic trigger unregulated
Tagcloud (Intersection) ?