RBM5 and ILF3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		RBM5	ILF3
Gene Name		RNA binding motif protein 5	interleukin enhancer binding factor 3, 90kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Apoptotic Process Negative Regulation Of Cell Proliferation RNA Splicing Gene Expression Positive Regulation Of Apoptotic Process	Transcription, DNA-templated Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		9 interactors: BCL2L1 GAPDH ILF3 LIG4 LRIF1 LSM8 WBP11 WDR77 ZDHHC17	26 interactors: DHX9 EIF2AK2 ERG FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MDFI NDRG1 PLSCR1 PRMT1 RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC TRIP6 XAB2 XPO5 ZNF346 ZNF830
Entrez ID		10181	3609
HPRD ID		06052	04420
Ensembl ID		ENSG00000003756	ENSG00000129351
Uniprot IDs		P52756	Q12906
PDB IDs		2LK0 2LK1 2LKZ	2L33 3P1X
Enriched GO Terms of Interacting Partners?		Neuron Apoptotic Process Neuron Death Response To Gamma Radiation RNA Splicing RNA Metabolic Process DNA Ligation Involved In DNA Recombination Peptidyl-cysteine S-trans-nitrosylation Apoptotic Process In Bone Marrow Negative Regulation Of Translation MRNA Processing MRNA Metabolic Process RNA Processing Response To Ionizing Radiation Suppression By Virus Of Host Apoptotic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Peptidyl-cysteine S-nitrosylation Negative Regulation Of Neuron Apoptotic Process Lagging Strand Elongation Pro-B Cell Differentiation Nucleobase-containing Compound Metabolic Process Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Negative Regulation Of Neuron Death Establishment Of Integrated Proviral Latency Positive Regulation Of Cell Proliferation Heterocycle Metabolic Process Negative Regulation Of Execution Phase Of Apoptosis Cellular Aromatic Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Neuron Apoptotic Process Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Response To Virus Cellular Nitrogen Compound Metabolic Process Regulation Of Translation Lymphoid Progenitor Cell Differentiation Apoptotic Process Gene Expression Cellular Response To Virus Regulation Of Neuron Death Modulation By Virus Of Host Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Programmed Cell Death Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane DNA Ligation Negative Regulation Of Anoikis Cell Death	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Regulation Of Female Gonad Development Ribonucleoprotein Complex Biogenesis Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Protein Import Into Nucleus Spliceosomal SnRNP Assembly Regulation Of Nitrogen Compound Metabolic Process MRNA Splice Site Selection Negative Regulation Of Viral Genome Replication Regulation Of Protein Localization To Nucleus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Evasion Or Tolerance By Virus Of Host Immune Response Negative Regulation Of Potassium Ion Export Regulation Of Nucleocytoplasmic Transport In Utero Embryonic Development Regulation Of RNA Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Intracellular Protein Transport Regulation Of Heart Rate By Hormone Interleukin-7-mediated Signaling Pathway Regulation Of Hematopoietic Stem Cell Differentiation Oocyte Growth Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Cellular Response To Stress Cellular Macromolecular Complex Assembly Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Intestinal Epithelial Structure Maintenance Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Transcription Factor Import Into Nucleus Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation
Tagcloud ?		accompanied active apoptotic apparently bax caspase cord demonstrating employed establish expressions immunofluorescent labeling localization location modulating motif nervous neuronal pc12 probe promotes regulating sci spinal suppressor traumatic trigger unregulated	acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored
Tagcloud (Difference) ?		accompanied active apoptotic apparently bax caspase cord demonstrating employed establish expressions immunofluorescent labeling localization location modulating motif nervous neuronal pc12 probe promotes regulating sci spinal suppressor traumatic trigger unregulated	acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored
Tagcloud (Intersection) ?