RBM5

Description		RNA binding motif protein 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing Apoptotic Process Negative Regulation Of Cell Population Proliferation RNA Splicing Positive Regulation Of Apoptotic Process
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Alanine aminotransferase levels ( 33547301) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Caffeine consumption from tea ( 33287642) Cortical surface area (MOSTest) ( 32665545) Dentures ( 31235808) Extremely high intelligence ( 29520040) HDL cholesterol ( 24097068) HDL cholesterol levels ( 30698716 28334899) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) Morning person ( 30696823) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		32 interacting genes: BCL2L1 CASK CIP2A CREBBP DCX DDX17 GAPDH ILF3 KIF19 KIF9 LIG4 LRIF1 LSM8 MED1 MEOX1 MEOX2 MIRLET7D MIRLET7E MIRLET7G MIRLET7I MLYCD NDEL1 PARD3B PCM1 PKP2 POMP RBM14 RNF10 SHANK3 WBP11 WDR77 ZDHHC17
Entrez ID		10181
HPRD ID		06052
Ensembl ID		ENSG00000003756
Uniprot IDs		P52756
PDB IDs		2LK0 2LK1 2LKZ 5MF9 5MFY 7PCV 7PDV
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Somite Specification Regulatory NcRNA-mediated Gene Silencing Kinesin Complex RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Microtubule Binding Post-transcriptional Gene Silencing Transcription Coactivator Activity Microtubule Cytoskeleton Organization Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell MRNA Base-pairing Post-transcriptional Repressor Activity Positive Regulation Of RNA Metabolic Process Organelle Organization Cytoplasm Segment Specification Somite Development Nuclear Retinoic Acid Receptor Binding RNA Splicing MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Ribonucleoprotein Complex RNA Splicing, Via Transesterification Reactions Hematopoietic Stem Cell Differentiation Post-transcriptional Regulation Of Gene Expression MRNA Metabolic Process Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Keratinocyte Proliferation Negative Regulation Of Gene Expression Neuron Apoptotic Process Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing
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