ALPL and EEF1A1

  • Number of citations of the paper that reports this interaction (PMID 16014383)
  • 4
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

ALPL

EEF1A1

Gene Name alkaline phosphatase, liver/bone/kidney eukaryotic translation elongation factor 1 alpha 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065)
  • Folate pathway vitamin levels ( 19303062 19744961)
  • Hematological and biochemical traits ( 20139978)
  • Liver enzyme levels ( 18940312)
  • Liver enzyme levels (alkaline phosphatase) ( 22001757)
  • Metabolic traits ( 21886157)
  • Phosphorus levels ( 20558539)
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
Protein-Protein Interactions 4 interactors: EEF1A1 MAP3K14 TRAF2 TRAF3 123 interactors: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCDC130 CCL18 CDC25A CDKN1A CKS2 COX17 CRADD CRCT1 CSRP2 DARS DIABLO DLEU1 DUSP7 DYNLL1 EIF3F EXOSC4 FAS GADD45A GADD45G GSK3B HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B KRAS LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP RAB27A RAP2A RBBP8 RFC5 RGS12 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB9 SFN SHBG SMAD2 SMAD4 SMN1 SNCA SPP1 SSR1 STAT6 STMN2 SULT1E1 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSPY1 TSPYL2 TTR UBQLN4 WARS XPO5 XRN2 YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1
Entrez ID 249 1915
HPRD ID 01377 00559
Ensembl ID ENSG00000162551 ENSG00000156508
Uniprot IDs P05186 P68104 Q6IPS9
PDB IDs 1SYW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abcc6  bmp2  bmps  calcification  comes  ectonucleotides  elasticum  enpp1  extrapolate  localizing  mineralisation  mineralization  msx2  multisystem  neovascularisation  osteoinductive  papular  perturbed  pseudoxanthoma  pxe  runx2  smad2  smads  stains  subretinal  tgfbeta  tgfbeta1  tgfbetas  whiskers 
akap6  atf7  atxn1  bmpr2  categorize  deltan  grip2  gtf2f1  interactors  jbd  jbds  jnk1alpha1  jnk3  jnk3alpha1  jnks  kcne4  myo9b  nnat  pias1  ptgds  ptpn2  rabgap1  rusc2  shank1  sumo1  sypl1  tkt  topbp1  znf668 
Tagcloud (Difference) ?
abcc6  bmp2  bmps  calcification  comes  ectonucleotides  elasticum  enpp1  extrapolate  localizing  mineralisation  mineralization  msx2  multisystem  neovascularisation  osteoinductive  papular  perturbed  pseudoxanthoma  pxe  runx2  smad2  smads  stains  subretinal  tgfbeta  tgfbeta1  tgfbetas  whiskers 
akap6  atf7  atxn1  bmpr2  categorize  deltan  grip2  gtf2f1  interactors  jbd  jbds  jnk1alpha1  jnk3  jnk3alpha1  jnks  kcne4  myo9b  nnat  pias1  ptgds  ptpn2  rabgap1  rusc2  shank1  sumo1  sypl1  tkt  topbp1  znf668 
Tagcloud (Intersection) ?