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MACF1 and CEP63
Number of citations of the paper that reports this interaction (PMID
17043677
)
96
Data Source:
BioGRID
(two hybrid)
MACF1
CEP63
Gene Name
microtubule-actin crosslinking factor 1
centrosomal protein 63kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Golgi Apparatus
Cytoskeleton
Microtubule
Plasma Membrane
Actin Cytoskeleton
Ruffle Membrane
Spindle Pole
Centrosome
Centriole
Cytosol
Molecular Function
Actin Binding
Calcium Ion Binding
Protein Binding
Microtubule Binding
ATPase Activity
Poly(A) RNA Binding
Actin Filament Binding
Protein Binding
Biological Process
Mesoderm Formation
Posttranslational Protein Targeting To Membrane
Movement Of Cell Or Subcellular Component
Cell Cycle Arrest
Establishment Or Maintenance Of Cell Polarity
Metabolic Process
Regulation Of Epithelial Cell Migration
Wnt Signaling Pathway
Positive Regulation Of Wnt Signaling Pathway
Regulation Of Microtubule-based Process
Wound Healing
Golgi To Plasma Membrane Protein Transport
Positive Regulation Of Axon Extension
Regulation Of Focal Adhesion Assembly
DNA Damage Checkpoint
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Organelle Organization
Mitotic Nuclear Division
Centriole Replication
Signal Transduction In Response To DNA Damage
Spindle Assembly
Cell Division
Pathways
Organelle biogenesis and maintenance
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
G2/M Transition
Assembly of the primary cilium
Centrosome maturation
Regulation of PLK1 Activity at G2/M Transition
Mitotic G2-G2/M phases
Anchoring of the basal body to the plasma membrane
Recruitment of mitotic centrosome proteins and complexes
Cell Cycle, Mitotic
Drugs
Diseases
GWAS
HDL cholesterol (
20686565
)
Height (
18391952
)
Protein-Protein Interactions
24 interactors:
ACTA1
APC
ATF7IP
CDC5L
CEP63
CNTNAP2
CNTNAP4
DISC1
DTNBP1
ESRRA
EXOC1
GOLGA4
JUN
MAPK9
MAPRE1
NRCAM
NRXN1
NRXN2
PLXND1
PRKCD
SKIL
TANGO6
TNIK
TRAF3IP1
44 interactors:
ALOX5
ARFIP2
ARNT2
CAMKK2
CCDC14
CCNI
CEP57
CEP57L1
DDX26B
DISC1
DST
DTNB
DZIP3
EXOC4
EZH2
FAM161A
FBF1
GSE1
HAUS1
KXD1
MACF1
MBIP
NCOR2
NDEL1
NXT2
PCNXL4
POLR3C
PPP1R13B
PPP4R1
SMARCE1
SMC3
SNRNP70
SPTAN1
SPTBN1
SSX3
SYNE1
SYT17
TANK
TBC1D15
TSHZ3
TXLNA
TXLNB
USHBP1
ZCCHC10
Entrez ID
23499
80254
HPRD ID
09750
07826
Ensembl ID
ENSG00000127603
ENSG00000182923
Uniprot IDs
Q6ZSD7
Q9UPN3
Q96MT8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nervous System Development
Generation Of Neurons
Neurogenesis
Regulation Of Cell Projection Organization
Cell Projection Organization
System Development
Developmental Process
Multicellular Organismal Development
Vocalization Behavior
Protein Localization
Regulation Of Cellular Component Organization
Cellular Localization
Neuron Projection Development
Anatomical Structure Development
Membrane Organization
Synapse Assembly
Neuroligin Clustering
Organelle Organization
Response To Mechanical Stimulus
Neuron Development
Cellular Protein Localization
Gephyrin Clustering
Cell Differentiation
Signaling
Cellular Component Assembly
Cell Communication
Negative Regulation Of Filopodium Assembly
Neuron Differentiation
Regulation Of Cell Differentiation
Social Behavior
Vocal Learning
Learning
Positive Regulation Of Cell Differentiation
Postsynaptic Membrane Assembly
Regulation Of Grooming Behavior
Synapse Organization
Cell Development
Regulation Of Neuron Projection Development
Postsynaptic Density Protein 95 Clustering
Anatomical Structure Formation Involved In Morphogenesis
Auditory Behavior
Movement Of Cell Or Subcellular Component
Regulation Of Signaling
Neuronal Ion Channel Clustering
Regulation Of Cell Morphogenesis
Neuron Cell-cell Adhesion
Positive Regulation Of Cell Development
Regulation Of Binding
Cell Projection Morphogenesis
Learning Or Memory
Microtubule Cytoskeleton Organization
Organelle Organization
Cytoskeleton Organization
Microtubule-based Process
Cell Cycle Process
Establishment Or Maintenance Of Cell Polarity
Negative Regulation Of Cell Cycle
Cellular Localization
Golgi To Plasma Membrane Protein Transport
Cell Cycle
Maintenance Of Protein Location In Cell
Maintenance Of Protein Location
Brain Development
Maintenance Of Location In Cell
Protein Localization To Organelle
Head Development
Anatomical Structure Development
Golgi To Plasma Membrane Transport
Regulation Of Cellular Component Size
Positive Regulation Of Axon Extension
Intermediate Filament Cytoskeleton Organization
Microtubule Anchoring
Protein Localization
Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway
Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Leukotriene Production Involved In Inflammatory Response
Kidney Smooth Muscle Cell Differentiation
Ureteric Peristalsis
Nervous System Development
Intermediate Filament-based Process
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Protein Localization To Nucleus
Regulation Of Cell Cycle
Cell Proliferation In Forebrain
Actin Filament Capping
Central Nervous System Development
Mitotic Cell Cycle Process
Cellular Protein Localization
Cerebral Cortex Radially Oriented Cell Migration
Endomembrane System Organization
Negative Regulation Of Actin Filament Depolymerization
Developmental Process
Tagcloud
?
a2
comprehensive
cytoskeleton
ecm
focal
genotypes
hbv
hbx
hcc
hepatocellular
hepg2
hmgb1
lamin
lc
migration
ms
nevertheless
obscure
platform
preliminary
profile
proteasome
proteomics
psma3
s100a11
s100a4
s100a6
supported
turn
Tagcloud (Difference)
?
a2
comprehensive
cytoskeleton
ecm
focal
genotypes
hbv
hbx
hcc
hepatocellular
hepg2
hmgb1
lamin
lc
migration
ms
nevertheless
obscure
platform
preliminary
profile
proteasome
proteomics
psma3
s100a11
s100a4
s100a6
supported
turn
Tagcloud (Intersection)
?