MACF1 and CNTNAP4

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		MACF1	CNTNAP4
Gene Name		microtubule-actin crosslinking factor 1	contactin associated protein-like 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytoskeleton Microtubule Plasma Membrane Actin Cytoskeleton Ruffle Membrane	Integral Component Of Membrane Cell Junction Dendrite Presynaptic Membrane
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Microtubule Binding ATPase Activity Poly(A) RNA Binding Actin Filament Binding
	Biological Process	Mesoderm Formation Posttranslational Protein Targeting To Membrane Movement Of Cell Or Subcellular Component Cell Cycle Arrest Establishment Or Maintenance Of Cell Polarity Metabolic Process Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Regulation Of Microtubule-based Process Wound Healing Golgi To Plasma Membrane Protein Transport Positive Regulation Of Axon Extension Regulation Of Focal Adhesion Assembly	Cell Adhesion Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Synaptic Transmission, GABAergic Regulation Of Grooming Behavior
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 20686565)	Response to amphetamines ( 22952603) Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225) Sphingolipid levels ( 22359512)
Protein-Protein Interactions		24 interactors: ACTA1 APC ATF7IP CDC5L CEP63 CNTNAP2 CNTNAP4 DISC1 DTNBP1 ESRRA EXOC1 GOLGA4 JUN MAPK9 MAPRE1 NRCAM NRXN1 NRXN2 PLXND1 PRKCD SKIL TANGO6 TNIK TRAF3IP1	6 interactors: APBA1 CASK FBXO21 MACF1 MAST3 RANBP10
Entrez ID		23499	85445
HPRD ID		09750	13079
Ensembl ID		ENSG00000127603	ENSG00000152910
Uniprot IDs		Q6ZSD7 Q9UPN3	Q9C0A0
PDB IDs
Enriched GO Terms of Interacting Partners?		Nervous System Development Generation Of Neurons Neurogenesis Regulation Of Cell Projection Organization Cell Projection Organization System Development Developmental Process Multicellular Organismal Development Vocalization Behavior Protein Localization Regulation Of Cellular Component Organization Cellular Localization Neuron Projection Development Anatomical Structure Development Membrane Organization Synapse Assembly Neuroligin Clustering Organelle Organization Response To Mechanical Stimulus Neuron Development Cellular Protein Localization Gephyrin Clustering Cell Differentiation Signaling Cellular Component Assembly Cell Communication Negative Regulation Of Filopodium Assembly Neuron Differentiation Regulation Of Cell Differentiation Social Behavior Vocal Learning Learning Positive Regulation Of Cell Differentiation Postsynaptic Membrane Assembly Regulation Of Grooming Behavior Synapse Organization Cell Development Regulation Of Neuron Projection Development Postsynaptic Density Protein 95 Clustering Anatomical Structure Formation Involved In Morphogenesis Auditory Behavior Movement Of Cell Or Subcellular Component Regulation Of Signaling Neuronal Ion Channel Clustering Regulation Of Cell Morphogenesis Neuron Cell-cell Adhesion Positive Regulation Of Cell Development Regulation Of Binding Cell Projection Morphogenesis Learning Or Memory
Tagcloud ?		a2 comprehensive cytoskeleton ecm focal genotypes hbv hbx hcc hepatocellular hepg2 hmgb1 lamin lc migration ms nevertheless obscure platform preliminary profile proteasome proteomics psma3 s100a11 s100a4 s100a6 supported turn
Tagcloud (Difference) ?		a2 comprehensive cytoskeleton ecm focal genotypes hbv hbx hcc hepatocellular hepg2 hmgb1 lamin lc migration ms nevertheless obscure platform preliminary profile proteasome proteomics psma3 s100a11 s100a4 s100a6 supported turn
Tagcloud (Intersection) ?